Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1267719..1268232 Replicon chromosome
Accession NZ_CP035299
Organism Corynebacterium pelargi strain 136/3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CPELA_RS05770 Protein ID WP_128889887.1
Coordinates 1267975..1268232 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CPELA_RS05765 Protein ID WP_128889886.1
Coordinates 1267719..1267973 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPELA_RS05735 1263053..1263523 + 471 WP_164931160.1 hypothetical protein -
CPELA_RS05745 1264840..1265334 - 495 WP_128889882.1 hypothetical protein -
CPELA_RS05750 1265794..1266705 - 912 WP_128889883.1 hypothetical protein -
CPELA_RS11060 1266986..1267342 + 357 WP_206731204.1 hypothetical protein -
CPELA_RS05760 1267296..1267631 + 336 WP_206731205.1 phosphatase PAP2 family protein -
CPELA_RS05765 1267719..1267973 + 255 WP_128889886.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CPELA_RS05770 1267975..1268232 + 258 WP_128889887.1 Txe/YoeB family addiction module toxin Toxin
CPELA_RS05775 1268556..1268648 + 93 WP_025402953.1 K(+)-transporting ATPase subunit F -
CPELA_RS05780 1268645..1270297 + 1653 WP_128889888.1 potassium-transporting ATPase subunit KdpA -
CPELA_RS05785 1270294..1272387 + 2094 WP_128889889.1 potassium-transporting ATPase subunit KdpB -
CPELA_RS05790 1272424..1273020 + 597 WP_128889890.1 potassium-transporting ATPase subunit KdpC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10337.60 Da        Isoelectric Point: 7.2751

>T117564 WP_128889887.1 NZ_CP035299:1267975-1268232 [Corynebacterium pelargi]
MLLVWDENAWEDYLWWQTQDRRTLKRINQLIKDIDRNSNEGIGKPEPLKHSLSGYWSRRITDEHRLVYSTIDSEIRIASC
RYHYG

Download         Length: 258 bp

>T117564 NZ_CP035299:1267975-1268232 [Corynebacterium pelargi]
ATGCTCTTAGTCTGGGATGAGAACGCTTGGGAAGACTACCTCTGGTGGCAAACCCAAGACCGCAGGACGTTGAAACGCAT
CAACCAACTCATCAAGGACATCGACCGCAATAGCAACGAGGGCATCGGGAAACCGGAACCGCTCAAGCACAGTTTGTCTG
GCTACTGGTCACGGCGCATCACTGATGAACATCGCCTGGTGTACAGCACAATAGACAGCGAGATTCGTATCGCGTCCTGC
CGCTACCACTACGGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9674.75 Da        Isoelectric Point: 4.5793

>AT117564 WP_128889886.1 NZ_CP035299:1267719-1267973 [Corynebacterium pelargi]
MKTMNYTESRANYAKVLDDVVNDREETIITRAGHESVVIVSLEEYESLKETAYLLRSPANARRLFESIDRLEANRGSEHS
LIEE

Download         Length: 255 bp

>AT117564 NZ_CP035299:1267719-1267973 [Corynebacterium pelargi]
ATGAAAACAATGAACTACACCGAGTCGCGGGCGAACTACGCCAAAGTCCTCGATGACGTGGTGAATGACCGCGAGGAAAC
GATCATCACCCGCGCAGGCCACGAATCAGTCGTTATCGTATCCCTGGAAGAATACGAATCCCTCAAAGAGACCGCCTACC
TGCTTCGATCCCCAGCCAATGCCCGTCGACTTTTCGAGTCGATAGACAGGCTCGAGGCAAACCGAGGCAGCGAGCACTCT
CTCATCGAGGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References