Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2489345..2489502 Replicon chromosome
Accession NZ_CP035294
Organism Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 strain ATCC 15305

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EQ030_RS12140 Protein ID WP_002441941.1
Coordinates 2489407..2489502 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2489345..2489378 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQ030_RS12115 2485133..2485966 + 834 WP_011304020.1 aldo/keto reductase -
EQ030_RS12120 2486433..2486732 - 300 WP_011304021.1 hypothetical protein -
EQ030_RS12125 2487109..2487342 + 234 WP_011304022.1 ferrous iron transport protein A -
EQ030_RS12130 2487403..2487468 - 66 WP_162009580.1 type I toxin-antitoxin system Fst family toxin -
EQ030_RS12135 2487656..2489056 - 1401 WP_011304023.1 RES family NAD+ phosphorylase -
- 2489345..2489378 + 34 - - Antitoxin
EQ030_RS12140 2489407..2489502 - 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
EQ030_RS12145 2489805..2490563 - 759 WP_011304024.1 MerR family transcriptional regulator -
EQ030_RS12150 2490673..2491236 - 564 WP_011304025.1 helix-turn-helix domain-containing protein -
EQ030_RS12155 2491430..2492887 - 1458 WP_011304026.1 carbon starvation protein A -
EQ030_RS12160 2493095..2493934 - 840 WP_002481957.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T117557 WP_002441941.1 NZ_CP035294:c2489502-2489407 [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp

>T117557 NZ_CP035294:c2489502-2489407 [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC]
ATGCTTATGATCTTCGTTCACATCATTGCACCAGTCATTAGTGGCTGTGCAGTTGCGTATTTTACTTATTGGCTTAGTAG
TAAACGCAATAAATAG

Antitoxin


Download         Length: 34 bp

>AT117557 NZ_CP035294:2489345-2489378 [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References