Detailed information of TA system TA117551

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2435691..2435839
• Replicon: chromosome
• Accession: NZ_CP035291
• Organism: Staphylococcus haemolyticus strain ATCC 29970

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: EQ029_RS11805
• Protein ID: WP_011276848.1
• Coordinates: 2435691..2435786 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2435804..2435839 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EQ029_RS11770	2431418..2431651	+	234	WP_016931184.1	hypothetical protein	-
EQ029_RS11775	2431759..2432076	-	318	Protein_2281	IS200/IS605-like element ISSep3 family transposase	-
EQ029_RS12630	2432769..2433026	+	258	Protein_2282	replication initiation protein	-
EQ029_RS11790	2433630..2434160	+	531	WP_011276845.1	N-acetyltransferase	-
EQ029_RS11795	2434400..2434783	+	384	WP_011276846.1	effector binding domain-containing protein	-
EQ029_RS11800	2434922..2435226	+	305	Protein_2285	hypothetical protein	-
EQ029_RS12635	2435350..2435496	+	147	WP_000668388.1	hypothetical protein	-
EQ029_RS11805	2435691..2435786	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2435804..2435839	+	36	-	-	Antitoxin
EQ029_RS11810	2435980..2436882	+	903	WP_057504751.1	nucleotidyltransferase	-
EQ029_RS11815	2436886..2437488	+	603	WP_011276850.1	hypothetical protein	-
EQ029_RS11820	2437632..2437715	-	84	Protein_2290	ATP-binding protein	-
EQ029_RS11825	2437716..2438252	-	537	WP_057504750.1	hypothetical protein	-
EQ029_RS11830	2438266..2438847	-	582	WP_011276564.1	TetR family transcriptional regulator C-terminal domain-containing protein	-
EQ029_RS11835	2439052..2439630	+	579	WP_037559009.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2431756..2432076	320

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T117551 WP_011276848.1 NZ_CP035291:2435691-2435786 [Staphylococcus haemolyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T117551 NZ_CP035291:2435691-2435786 [Staphylococcus haemolyticus]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT117551 NZ_CP035291:2435804-2435839 [Staphylococcus haemolyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin