Detailed information of TA system TA117409

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2243106..2243323
• Replicon: chromosome
• Accession: NZ_CP035226
• Organism: Bacillus subtilis strain SRCM103517

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: EQW70_RS11690
• Protein ID: WP_032721653.1
• Coordinates: 2243147..2243323 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2243106..2243206 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EQW70_RS22205	2238440..2238598	-	159	WP_164914267.1	hypothetical protein	-
EQW70_RS11630	2238633..2238839	-	207	WP_128740466.1	hypothetical protein	-
EQW70_RS11635	2238868..2239089	-	222	WP_128740467.1	hypothetical protein	-
EQW70_RS11640	2239076..2239339	-	264	WP_128740468.1	hypothetical protein	-
EQW70_RS11645	2239354..2239590	-	237	WP_128740469.1	hypothetical protein	-
EQW70_RS11650	2239590..2239784	-	195	WP_128740470.1	hypothetical protein	-
EQW70_RS11655	2239820..2240131	-	312	WP_128740471.1	hypothetical protein	-
EQW70_RS11660	2240156..2240377	-	222	WP_128740472.1	hypothetical protein	-
EQW70_RS11665	2240533..2240736	-	204	WP_124048602.1	hypothetical protein	-
EQW70_RS11670	2240800..2241003	-	204	WP_128740473.1	hypothetical protein	-
EQW70_RS11675	2241345..2242562	-	1218	WP_128740474.1	hypothetical protein	-
EQW70_RS11680	2242644..2242832	-	189	WP_003230987.1	hypothetical protein	-
EQW70_RS11685	2242877..2243128	-	252	WP_080010576.1	hypothetical protein	-
-	2243106..2243206	+	101	-	-	Antitoxin
EQW70_RS11690	2243147..2243323	-	177	WP_032721653.1	hypothetical protein	Toxin
-	2243264..2243364	+	101	NuclAT_0	-	-
-	2243264..2243364	+	101	NuclAT_0	-	-
-	2243264..2243364	+	101	NuclAT_0	-	-
-	2243264..2243364	+	101	NuclAT_0	-	-
EQW70_RS11700	2243857..2244468	-	612	WP_128740475.1	hypothetical protein	-
EQW70_RS11705	2244663..2244989	-	327	WP_128740476.1	helix-turn-helix domain-containing protein	-
EQW70_RS11710	2245941..2246135	+	195	WP_072692657.1	hypothetical protein	-
EQW70_RS11715	2246175..2248049	+	1875	Protein_2241	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2173775..2309084	135309

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T117409 WP_032721653.1 NZ_CP035226:c2243323-2243147 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T117409 NZ_CP035226:c2243323-2243147 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCAGATGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT117409 NZ_CP035226:2243106-2243206 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCTGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin