Detailed information of TA system TA117284

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2564649..2564974
• Replicon: chromosome
• Accession: NZ_CP035166
• Organism: Bacillus subtilis strain SRCM103971

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: EQI87_RS13445
• Protein ID: WP_004398662.1
• Coordinates: 2564649..2564828 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2564752..2564974 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EQI87_RS13435	2563875..2564012	-	138	WP_021480099.1	hypothetical protein	-
EQI87_RS13440	2564054..2564503	-	450	WP_032722171.1	phage portal protein	-
EQI87_RS13445	2564649..2564828	+	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2564752..2564974	-	223	NuclAT_0	-	Antitoxin
-	2564752..2564974	-	223	NuclAT_0	-	Antitoxin
-	2564752..2564974	-	223	NuclAT_0	-	Antitoxin
-	2564752..2564974	-	223	NuclAT_0	-	Antitoxin
EQI87_RS13450	2565208..2565297	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
EQI87_RS13455	2565551..2565994	-	444	WP_003229930.1	phage tail tube protein	-
EQI87_RS13460	2565997..2567397	-	1401	WP_003229929.1	phage tail sheath family protein	-
EQI87_RS13465	2567398..2567589	-	192	WP_010886574.1	hypothetical protein	-
EQI87_RS13470	2567586..2568023	-	438	WP_003229927.1	hypothetical protein	-
EQI87_RS13475	2568036..2568539	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
EQI87_RS13480	2568536..2568898	-	363	WP_003229925.1	YqbH/XkdH family protein	-
EQI87_RS13485	2568895..2569290	-	396	WP_004398566.1	DUF3199 family protein	-
EQI87_RS13490	2569294..2569605	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2534072..2594012	59940

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T117284 WP_004398662.1 NZ_CP035166:2564649-2564828 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T117284 NZ_CP035166:2564649-2564828 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT117284 NZ_CP035166:c2564974-2564752 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin