Detailed information of TA system TA117271

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2185728..2185945
• Replicon: chromosome
• Accession: NZ_CP035165
• Organism: Bacillus subtilis strain SRCM103881

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: EQI56_RS11225
• Protein ID: WP_032721653.1
• Coordinates: 2185769..2185945 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2185728..2185828 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EQI56_RS11175	2180862..2181299	-	438	WP_114168600.1	hypothetical protein	-
EQI56_RS11180	2181390..2181773	-	384	WP_114168681.1	UPF0715 family protein	-
EQI56_RS11185	2181853..2182188	-	336	WP_114168602.1	hypothetical protein	-
EQI56_RS11190	2182226..2182522	-	297	WP_114168604.1	hypothetical protein	-
EQI56_RS11195	2182598..2182843	-	246	WP_114168606.1	hypothetical protein	-
EQI56_RS11200	2183042..2183323	-	282	WP_050496376.1	hypothetical protein	-
EQI56_RS11205	2183357..2183611	-	255	WP_100244913.1	hypothetical protein	-
EQI56_RS11210	2183967..2185184	-	1218	WP_114168608.1	hypothetical protein	-
EQI56_RS11215	2185266..2185454	-	189	WP_114168610.1	hypothetical protein	-
EQI56_RS11220	2185499..2185750	-	252	WP_080010576.1	hypothetical protein	-
-	2185728..2185828	+	101	-	-	Antitoxin
EQI56_RS11225	2185769..2185945	-	177	WP_032721653.1	hypothetical protein	Toxin
-	2185886..2185986	+	101	NuclAT_0	-	-
-	2185886..2185986	+	101	NuclAT_0	-	-
-	2185886..2185986	+	101	NuclAT_0	-	-
-	2185886..2185986	+	101	NuclAT_0	-	-
EQI56_RS11230	2186900..2187094	+	195	WP_003230986.1	hypothetical protein	-
EQI56_RS11235	2187134..2189653	+	2520	WP_019712270.1	hypothetical protein	-
EQI56_RS11240	2189897..2190175	+	279	WP_004399274.1	HU-related DNA-binding protein HupN	-
EQI56_RS11245	2190745..2190915	+	171	WP_128472249.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2116141..2264885	148744

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T117271 WP_032721653.1 NZ_CP035165:c2185945-2185769 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T117271 NZ_CP035165:c2185945-2185769 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT117271 NZ_CP035165:2185728-2185828 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin