Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2550607..2550932 | Replicon | chromosome |
Accession | NZ_CP035163 | ||
Organism | Bacillus subtilis strain SRCM103923 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | P54373 |
Locus tag | EQI27_RS13240 | Protein ID | WP_004398662.1 |
Coordinates | 2550607..2550786 (+) | Length | 60 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2550710..2550932 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EQI27_RS13230 | 2549833..2549970 | - | 138 | WP_021480099.1 | hypothetical protein | - |
EQI27_RS13235 | 2550012..2550461 | - | 450 | WP_032722171.1 | phage portal protein | - |
EQI27_RS13240 | 2550607..2550786 | + | 180 | WP_004398662.1 | type I toxin-antitoxin system toxin TxpA | Toxin |
- | 2550710..2550932 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2550710..2550932 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2550710..2550932 | - | 223 | NuclAT_0 | - | Antitoxin |
- | 2550710..2550932 | - | 223 | NuclAT_0 | - | Antitoxin |
EQI27_RS13245 | 2551166..2551255 | + | 90 | WP_075058862.1 | type I toxin-antitoxin system toxin BsrH | - |
EQI27_RS13250 | 2551509..2551952 | - | 444 | WP_003229930.1 | phage tail tube protein | - |
EQI27_RS13255 | 2551955..2553354 | - | 1400 | Protein_2542 | phage tail sheath family protein | - |
EQI27_RS13260 | 2553355..2553546 | - | 192 | WP_010886574.1 | hypothetical protein | - |
EQI27_RS13265 | 2553543..2553980 | - | 438 | WP_003229927.1 | hypothetical protein | - |
EQI27_RS13270 | 2553993..2554496 | - | 504 | WP_003246050.1 | HK97 gp10 family phage protein | - |
EQI27_RS13275 | 2554493..2554855 | - | 363 | WP_003229925.1 | YqbH/XkdH family protein | - |
EQI27_RS13280 | 2554852..2555247 | - | 396 | WP_004398566.1 | DUF3199 family protein | - |
EQI27_RS13285 | 2555251..2555562 | - | 312 | WP_003229923.1 | YqbF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2525359..2575481 | 50122 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 60 a.a. Molecular weight: 6739.19 Da Isoelectric Point: 8.0370
>T117260 WP_004398662.1 NZ_CP035163:2550607-2550786 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG
Download Length: 180 bp
>T117260 NZ_CP035163:2550607-2550786 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG
Antitoxin
Download Length: 223 bp
>AT117260 NZ_CP035163:c2550932-2550710 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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