Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 183369..183874 Replicon chromosome
Accession NZ_CP035129
Organism Kosakonia cowanii strain FBS 223

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EQG67_RS00890 Protein ID WP_128481917.1
Coordinates 183614..183874 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EQG67_RS00885 Protein ID WP_054802741.1
Coordinates 183369..183617 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQG67_RS00865 179867..180313 - 447 WP_128481914.1 N-acetyltransferase -
EQG67_RS00870 180291..180872 - 582 WP_076769345.1 DNA-3-methyladenine glycosylase I -
EQG67_RS00875 181020..181700 + 681 WP_128481915.1 autotransporter domain-containing protein -
EQG67_RS00880 181942..183144 + 1203 WP_128481916.1 MFS transporter -
EQG67_RS00885 183369..183617 + 249 WP_054802741.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EQG67_RS00890 183614..183874 + 261 WP_128481917.1 Txe/YoeB family addiction module toxin Toxin
EQG67_RS00895 183978..184409 + 432 WP_042718589.1 organic hydroperoxide resistance protein -
EQG67_RS00900 184624..186306 + 1683 WP_128481918.1 kdo(2)-lipid A phosphoethanolamine 7''-transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10276.90 Da        Isoelectric Point: 9.6929

>T117236 WP_128481917.1 NZ_CP035129:183614-183874 [Kosakonia cowanii]
MTPRITPEAQADIDFWKQNDPKVKQKIDTLVRDALEHPFQGLGKPEALKYHKPLWSRRITKEHRLVYYIKDDSLIIVSCR
YHYVNL

Download         Length: 261 bp

>T117236 NZ_CP035129:183614-183874 [Kosakonia cowanii]
ATGACGCCCAGGATAACGCCGGAAGCGCAAGCTGATATAGATTTCTGGAAGCAGAACGACCCTAAGGTAAAGCAGAAGAT
TGATACCCTCGTCAGGGATGCGCTTGAGCACCCTTTTCAGGGGCTCGGAAAGCCGGAAGCGCTTAAGTACCATAAACCGC
TCTGGTCGCGCCGCATCACCAAAGAGCATCGTCTCGTTTACTACATAAAAGATGACTCGCTGATTATCGTTTCTTGCCGC
TACCACTACGTAAATCTTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9217.28 Da        Isoelectric Point: 4.5298

>AT117236 WP_054802741.1 NZ_CP035129:183369-183617 [Kosakonia cowanii]
MQHVNYTDARQNLASLMQQANDELAPILVTRKGAKSVVVIDAEEFASMQETLHLFSNPVNAAHIERSIQQAESGDLQEYK
FE

Download         Length: 249 bp

>AT117236 NZ_CP035129:183369-183617 [Kosakonia cowanii]
ATGCAACATGTTAACTACACCGACGCCCGCCAGAACCTGGCCTCGCTGATGCAGCAGGCAAATGACGAGCTGGCACCGAT
CCTTGTCACCCGCAAAGGGGCTAAAAGCGTGGTGGTTATCGATGCCGAGGAGTTTGCCTCTATGCAAGAGACGCTTCATC
TGTTCAGTAATCCGGTCAACGCCGCGCATATTGAGCGCAGCATCCAACAGGCGGAAAGCGGCGACCTACAGGAATATAAA
TTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References