Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1109937..1110592 Replicon chromosome
Accession NZ_CP035088
Organism Pseudomonas viciae strain 11K1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EPZ47_RS04905 Protein ID WP_092223719.1
Coordinates 1109937..1110281 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EPZ47_RS04910 Protein ID WP_135843777.1
Coordinates 1110278..1110592 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPZ47_RS04880 1104952..1105899 + 948 WP_135843773.1 ubiquinol oxidase subunit II -
EPZ47_RS04885 1105903..1107933 + 2031 WP_135843774.1 cytochrome o ubiquinol oxidase subunit I -
EPZ47_RS04890 1107937..1108563 + 627 WP_135843775.1 cytochrome o ubiquinol oxidase subunit III -
EPZ47_RS04895 1108564..1108899 + 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
EPZ47_RS04900 1108911..1109798 + 888 WP_135843776.1 heme o synthase -
EPZ47_RS04905 1109937..1110281 + 345 WP_092223719.1 toxin Toxin
EPZ47_RS04910 1110278..1110592 + 315 WP_135843777.1 helix-turn-helix domain-containing protein Antitoxin
EPZ47_RS04915 1110701..1111405 - 705 WP_135843778.1 hypothetical protein -
EPZ47_RS04920 1111565..1112578 - 1014 WP_135843779.1 diguanylate cyclase -
EPZ47_RS04925 1112678..1113595 - 918 WP_135843780.1 LysR family transcriptional regulator -
EPZ47_RS04930 1113694..1114869 + 1176 WP_135843781.1 aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13709.71 Da        Isoelectric Point: 9.2887

>T117178 WP_092223719.1 NZ_CP035088:1109937-1110281 [Pseudomonas viciae]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLQHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T117178 NZ_CP035088:1109937-1110281 [Pseudomonas viciae]
ATGCGTACCCTGTTTTTTGAAACGACTACGTTCACCGCCACGGTTGGCCATTACCTGACTGACGATGAATATCGCCTGCT
TCAGTCCTATATGCTGCAGCATCCAGAGGTCGGTGACGTCATGCCACGTACTGGCGGCTTTCGTAAGCTGCGCTGGTTCG
ATGAACGTCGTGGTAAAGGGAAGCGCGGTGGGTTGCGAGTCATTTACTATTGGCTCATGAACGATCGTCAGTTTTGGATG
TTCGCGATTTATGACAAGGACGAGTTGGAAAACCTGACCTCCGAGCAAGAGAAGACGCTCAAGCGCGCCATAGAAGCTGA
GTTGAAAGTACGAGGTACCTTATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11731.65 Da        Isoelectric Point: 9.8409

>AT117178 WP_135843777.1 NZ_CP035088:1110278-1110592 [Pseudomonas viciae]
MKKRDLFAEMMQGVEEMAAHREGKITLRQTSIEDKPAPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT117178 NZ_CP035088:1110278-1110592 [Pseudomonas viciae]
ATGAAAAAGCGCGATCTGTTTGCCGAGATGATGCAAGGCGTCGAGGAGATGGCCGCTCACCGCGAGGGCAAGATTACCCT
TCGCCAGACATCGATCGAAGACAAACCGGCTCCCGAGGTATCGGCCCAGGAAATCGTGGCTTTGCGCGACAAGCTCCACA
TGTCTCAAGCCGTTTTCGCCAAGAGCATCAGGACCAGTCCAGGTACCCTGAGAAATTGGGAACAGGAAAAATCCAAGCCT
AACGCCCAGGCGGCTTTGTTGATCAAACTGGTCGAGAAGTTTCCAGACATGGTTGAACGGCTTGGCGCTGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References