Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4137841..4138496 Replicon chromosome
Accession NZ_CP035042
Organism Halomonas sp. BC-M4-5

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EKK97_RS19215 Protein ID WP_159554384.1
Coordinates 4137841..4138179 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EKK97_RS19220 Protein ID WP_201296930.1
Coordinates 4138176..4138496 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKK97_RS19185 4133434..4133835 - 402 WP_159554376.1 SgcJ/EcaC family oxidoreductase -
EKK97_RS19190 4134243..4134572 - 330 WP_159554378.1 hypothetical protein -
EKK97_RS23980 4134789..4135106 - 318 WP_201296929.1 hypothetical protein -
EKK97_RS19200 4135497..4136243 + 747 WP_201297147.1 ion transporter -
EKK97_RS19205 4136262..4137524 + 1263 WP_159554382.1 DUF4236 domain-containing protein -
EKK97_RS19215 4137841..4138179 + 339 WP_159554384.1 toxin Toxin
EKK97_RS19220 4138176..4138496 + 321 WP_201296930.1 transcriptional regulator Antitoxin
EKK97_RS19225 4138509..4139375 - 867 WP_159554388.1 hypothetical protein -
EKK97_RS19230 4139448..4140461 - 1014 WP_201296931.1 sensor domain-containing diguanylate cyclase -
EKK97_RS19235 4140688..4141329 + 642 WP_159554390.1 DsbA family oxidoreductase -
EKK97_RS19240 4141512..4141916 - 405 WP_159554392.1 GFA family protein -
EKK97_RS19245 4142060..4142371 - 312 WP_159554394.1 hypothetical protein -
EKK97_RS19250 4142368..4143099 - 732 WP_201296932.1 AzlC family ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-102)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13018.81 Da        Isoelectric Point: 10.4460

>T117160 WP_159554384.1 NZ_CP035042:4137841-4138179 [Halomonas sp. BC-M4-5]
MKAIFVELPPFERHRSTYFDDAAFRAFQNFLLQNPGAGDVIQGTGGLRKVRFSDPKRQKGKRGGVRIIYYWWLGGSQFWL
FTLYDKDSQDDLTTAQRKTLRQLLDAEINART

Download         Length: 339 bp

>T117160 NZ_CP035042:4137841-4138179 [Halomonas sp. BC-M4-5]
ATGAAAGCCATATTTGTCGAGCTGCCACCCTTCGAGCGGCACCGTTCCACCTACTTCGATGACGCCGCCTTTCGTGCCTT
CCAGAATTTCTTGCTTCAGAACCCTGGGGCCGGTGACGTCATCCAAGGAACAGGCGGGCTGCGCAAGGTCCGGTTCAGTG
ATCCCAAGCGGCAGAAGGGAAAGCGGGGCGGTGTTCGCATCATTTACTACTGGTGGCTGGGAGGCTCCCAGTTCTGGCTG
TTCACCCTGTACGACAAGGATTCACAGGATGACCTCACGACAGCCCAGCGCAAGACCCTGAGACAGCTGCTGGATGCGGA
AATCAACGCGAGGACATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12258.02 Da        Isoelectric Point: 6.0894

>AT117160 WP_201296930.1 NZ_CP035042:4138176-4138496 [Halomonas sp. BC-M4-5]
MTMGRNIFDELIEGFDALADERHGKRTLRSHSVELAEVPDVTASELIELRERLHMSRPVFAMYLRTNPRTLENWEQGRAK
PNAQAMTLIRLVQKYPETLEHLADLA

Download         Length: 321 bp

>AT117160 NZ_CP035042:4138176-4138496 [Halomonas sp. BC-M4-5]
ATGACCATGGGCCGTAACATTTTTGATGAACTCATCGAGGGCTTCGATGCATTGGCAGATGAGCGCCATGGCAAGCGCAC
GCTACGCTCCCACTCCGTAGAGCTGGCAGAGGTTCCCGACGTCACAGCCAGCGAGCTCATCGAGCTGCGGGAGCGGCTGC
ATATGTCCCGCCCGGTTTTCGCCATGTACCTCCGCACCAACCCAAGGACGCTGGAGAATTGGGAGCAAGGCCGCGCCAAG
CCCAATGCCCAGGCCATGACACTCATCCGGCTGGTCCAGAAGTATCCTGAAACCCTCGAGCATCTCGCTGATCTTGCCTA
G

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References