117134

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2610685..2610869 Replicon chromosome
Accession NZ_CP035005
Organism Staphylococcus aureus strain PCFH-226

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EMO94_RS13330 Protein ID WP_000482647.1
Coordinates 2610685..2610792 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2610809..2610869 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EMO94_RS13305 2606042..2606515 + 474 WP_000456489.1 GyrI-like domain-containing protein -
EMO94_RS13310 2606638..2607849 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
EMO94_RS13315 2608037..2608696 - 660 WP_000831300.1 hypothetical protein -
EMO94_RS13320 2608756..2609898 - 1143 WP_001176859.1 glycerate kinase -
EMO94_RS13325 2610165..2610551 + 387 WP_000779355.1 flippase GtxA -
EMO94_RS13330 2610685..2610792 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2610809..2610869 - 61 - - Antitoxin
EMO94_RS13340 2611496..2613259 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
EMO94_RS13345 2613284..2615017 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
EMO94_RS13355 2615248..2615415 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T117134 WP_000482647.1 NZ_CP035005:2610685-2610792 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T117134 NZ_CP035005:2610685-2610792 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT117134 NZ_CP035005:c2610869-2610809 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References