117123

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1273337..1273521 Replicon chromosome
Accession NZ_CP035003
Organism Staphylococcus aureus strain PCFA-221

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EMO93_RS06550 Protein ID WP_000482647.1
Coordinates 1273414..1273521 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1273337..1273397 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EMO93_RS06525 1268791..1268958 - 168 WP_001798790.1 hypothetical protein -
EMO93_RS06535 1269189..1270922 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
EMO93_RS06540 1270947..1272710 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 1273337..1273397 + 61 - - Antitoxin
EMO93_RS06550 1273414..1273521 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EMO93_RS06555 1273655..1274041 - 387 WP_000779355.1 flippase GtxA -
EMO93_RS06560 1274308..1275450 + 1143 WP_001176859.1 glycerate kinase -
EMO93_RS06565 1275510..1276169 + 660 WP_000831300.1 hypothetical protein -
EMO93_RS06570 1276357..1277568 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
EMO93_RS06575 1277691..1278164 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T117123 WP_000482647.1 NZ_CP035003:c1273521-1273414 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T117123 NZ_CP035003:c1273521-1273414 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT117123 NZ_CP035003:1273337-1273397 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References