117121

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 977554..977817 Replicon chromosome
Accession NZ_CP035003
Organism Staphylococcus aureus strain PCFA-221

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EMO93_RS04940 Protein ID WP_001802298.1
Coordinates 977713..977817 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 977554..977718 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EMO93_RS04920 973805..974470 - 666 WP_001024099.1 SDR family oxidoreductase -
EMO93_RS04925 974622..974942 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EMO93_RS04930 974944..975924 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
EMO93_RS04935 976190..977281 + 1092 WP_000495673.1 hypothetical protein -
- 977554..977718 + 165 - - Antitoxin
EMO93_RS04940 977713..977817 - 105 WP_001802298.1 hypothetical protein Toxin
EMO93_RS04955 978497..978655 + 159 WP_001792784.1 hypothetical protein -
EMO93_RS04960 979091..979183 + 93 WP_000220902.1 hypothetical protein -
EMO93_RS04965 979313..980170 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
EMO93_RS04970 980238..981020 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
EMO93_RS04975 981310..981918 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T117121 WP_001802298.1 NZ_CP035003:c977817-977713 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T117121 NZ_CP035003:c977817-977713 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT117121 NZ_CP035003:977554-977718 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References