Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | symER/SymE(toxin) |
Location | 1386792..1387204 | Replicon | chromosome |
Accession | NZ_CP034808 | ||
Organism | Escherichia coli strain 08-3914 |
Toxin (Protein)
Gene name | symE | Uniprot ID | Q8FA88 |
Locus tag | AYP36_RS06615 | Protein ID | WP_000132630.1 |
Coordinates | 1386863..1387204 (+) | Length | 114 a.a. |
Antitoxin (RNA)
Gene name | symR | ||
Locus tag | - | ||
Coordinates | 1386792..1386868 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AYP36_RS06605 | 1383419..1384888 | + | 1470 | WP_001302468.1 | type I restriction-modification system subunit M | - |
AYP36_RS06610 | 1384888..1386642 | + | 1755 | WP_000110082.1 | restriction endonuclease subunit S | - |
- | 1386792..1386868 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_15 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_15 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_15 | - | Antitoxin |
- | 1386792..1386868 | - | 77 | NuclAT_15 | - | Antitoxin |
AYP36_RS06615 | 1386863..1387204 | + | 342 | WP_000132630.1 | endoribonuclease SymE | Toxin |
AYP36_RS06620 | 1387251..1388414 | - | 1164 | WP_001304006.1 | DUF1524 domain-containing protein | - |
AYP36_RS06625 | 1388462..1389343 | - | 882 | WP_001304007.1 | DUF262 domain-containing protein | - |
AYP36_RS06630 | 1389440..1389604 | - | 165 | WP_000394274.1 | DUF1127 domain-containing protein | - |
AYP36_RS06635 | 1389781..1391193 | + | 1413 | WP_000199295.1 | PLP-dependent aminotransferase family protein | - |
AYP36_RS28905 | 1391436..1391636 | - | 201 | WP_001310455.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | espX6 | 1378991..1400200 | 21209 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12294.13 Da Isoelectric Point: 8.4982
>T116836 WP_000132630.1 NZ_CP034808:1386863-1387204 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
Download Length: 342 bp
>T116836 NZ_CP034808:1386863-1387204 [Escherichia coli]
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
Antitoxin
Download Length: 77 bp
>AT116836 NZ_CP034808:c1386868-1386792 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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