Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | symER/SymE(toxin) |
Location | 1397970..1398382 | Replicon | chromosome |
Accession | NZ_CP034801 | ||
Organism | Escherichia coli strain 2010C-3142 |
Toxin (Protein)
Gene name | symE | Uniprot ID | Q8FA88 |
Locus tag | AYR10_RS06700 | Protein ID | WP_000132630.1 |
Coordinates | 1398041..1398382 (+) | Length | 114 a.a. |
Antitoxin (RNA)
Gene name | symR | ||
Locus tag | - | ||
Coordinates | 1397970..1398046 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AYR10_RS06690 | 1394597..1396066 | + | 1470 | WP_001302468.1 | type I restriction-modification system subunit M | - |
AYR10_RS06695 | 1396066..1397820 | + | 1755 | WP_000110082.1 | restriction endonuclease subunit S | - |
- | 1397970..1398046 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_14 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_15 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_15 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_15 | - | Antitoxin |
- | 1397970..1398046 | - | 77 | NuclAT_15 | - | Antitoxin |
AYR10_RS06700 | 1398041..1398382 | + | 342 | WP_000132630.1 | endoribonuclease SymE | Toxin |
AYR10_RS06705 | 1398429..1399592 | - | 1164 | WP_001304006.1 | DUF1524 domain-containing protein | - |
AYR10_RS06710 | 1399640..1400521 | - | 882 | WP_001304007.1 | DUF262 domain-containing protein | - |
AYR10_RS06715 | 1400618..1400782 | - | 165 | WP_000394274.1 | DUF1127 domain-containing protein | - |
AYR10_RS06720 | 1400959..1402371 | + | 1413 | WP_000199295.1 | PLP-dependent aminotransferase family protein | - |
AYR10_RS28595 | 1402614..1402814 | - | 201 | WP_001310455.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | espX6 | 1390169..1411383 | 21214 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12294.13 Da Isoelectric Point: 8.4982
>T116726 WP_000132630.1 NZ_CP034801:1398041-1398382 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
Download Length: 342 bp
>T116726 NZ_CP034801:1398041-1398382 [Escherichia coli]
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA
Antitoxin
Download Length: 77 bp
>AT116726 NZ_CP034801:c1398046-1397970 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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