Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 5212791..5213491 Replicon chromosome
Accession NZ_CP034783
Organism Pseudomonas sp. MPC6

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag ELQ88_RS26075 Protein ID WP_138968650.1
Coordinates 5212791..5213087 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag ELQ88_RS26080 Protein ID WP_138968652.1
Coordinates 5213090..5213491 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELQ88_RS26050 5208677..5209033 + 357 WP_128871738.1 4a-hydroxytetrahydrobiopterin dehydratase -
ELQ88_RS26055 5209033..5210226 + 1194 WP_128871739.1 aspartate/tyrosine/aromatic aminotransferase -
ELQ88_RS26060 5210730..5210966 + 237 WP_178084712.1 hypothetical protein -
ELQ88_RS26065 5211067..5212281 + 1215 WP_138968648.1 MFS transporter -
ELQ88_RS26070 5212278..5212691 - 414 WP_008010994.1 aminoacyl-tRNA hydrolase -
ELQ88_RS26075 5212791..5213087 + 297 WP_138968650.1 type II toxin-antitoxin system MqsR family toxin Toxin
ELQ88_RS26080 5213090..5213491 + 402 WP_138968652.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
ELQ88_RS26085 5213566..5214261 - 696 WP_138968654.1 pentapeptide repeat-containing protein -
ELQ88_RS26090 5214364..5215782 - 1419 WP_138968656.1 amino acid permease -
ELQ88_RS26095 5216644..5217942 - 1299 WP_128871742.1 pseudouridine synthase -
ELQ88_RS26100 5218098..5218289 - 192 WP_128871743.1 DUF1289 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10965.86 Da        Isoelectric Point: 6.7074

>T116516 WP_138968650.1 NZ_CP034783:5212791-5213087 [Pseudomonas sp. MPC6]
MEKRIPHCKLSTVKVLIEAGKVRTTQAARVGAVELGLDLCEMLTVVMALTPTDFYKSMTTHADHTIWQDVYRPSTQAGDV
YLKLTVIDDVLIVSFKEL

Download         Length: 297 bp

>T116516 NZ_CP034783:5212791-5213087 [Pseudomonas sp. MPC6]
ATGGAAAAAAGAATCCCTCACTGCAAGCTATCTACCGTAAAAGTCTTGATTGAGGCGGGCAAGGTACGTACCACGCAAGC
GGCTCGCGTTGGAGCGGTTGAGTTGGGGCTTGATCTTTGCGAGATGCTGACGGTGGTAATGGCGCTTACACCCACTGATT
TTTACAAAAGCATGACCACTCACGCCGACCACACGATTTGGCAAGACGTGTACCGCCCGAGCACACAAGCAGGTGACGTG
TATCTGAAACTGACGGTTATTGATGACGTGCTGATCGTATCCTTTAAGGAGCTATAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14631.97 Da        Isoelectric Point: 7.0830

>AT116516 WP_138968652.1 NZ_CP034783:5213090-5213491 [Pseudomonas sp. MPC6]
MKCPVCGAAELIHDTRDLPYTYKGETTVIAAVMGDFCPACTESVLGAAESDRVMREMRAFTKQINAAIVDPGFITTVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLKVLDRHPELLNEVKAY

Download         Length: 402 bp

>AT116516 NZ_CP034783:5213090-5213491 [Pseudomonas sp. MPC6]
ATGAAATGTCCTGTTTGCGGCGCAGCTGAACTCATCCATGACACCCGCGACCTGCCGTATACCTACAAAGGTGAAACCAC
TGTCATTGCGGCGGTGATGGGCGACTTCTGCCCCGCCTGTACCGAATCAGTTTTGGGTGCAGCTGAGTCGGATCGTGTCA
TGCGTGAAATGCGTGCTTTCACCAAGCAAATCAATGCGGCCATTGTCGATCCGGGTTTTATCACGACCGTACGCAAAAAG
CTCGATCTTGACCAGCGTGAAGCGGCTGAGATTTTCGGCGGCGGCGTCAATGCATTCTCGCGCTATGAGAATGGCAAGAC
CAAGCCCCCATTGGCTCTGGTCAAGCTGCTCAAGGTGCTTGATCGTCACCCGGAGCTGTTGAACGAAGTCAAAGCGTATT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References