Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 262817..263516 Replicon plasmid pMPC6-328K
Accession NZ_CP034782
Organism Pseudomonas sp. MPC6

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag ELQ88_RS01555 Protein ID WP_138963208.1
Coordinates 263220..263516 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag ELQ88_RS01550 Protein ID WP_138963206.1
Coordinates 262817..263218 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELQ88_RS01525 258126..259136 - 1011 WP_138963200.1 D-cysteine desulfhydrase -
ELQ88_RS01530 259278..260189 + 912 WP_138963202.1 LysR family transcriptional regulator -
ELQ88_RS01535 261015..261788 - 774 WP_138963204.1 sulfite exporter TauE/SafE family protein -
ELQ88_RS34265 261891..262136 - 246 WP_178084664.1 hypothetical protein -
ELQ88_RS01545 262261..262578 - 318 Protein_245 transposase -
ELQ88_RS01550 262817..263218 - 402 WP_138963206.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
ELQ88_RS01555 263220..263516 - 297 WP_138963208.1 type II toxin-antitoxin system MqsR family toxin Toxin
ELQ88_RS01560 263844..264143 + 300 WP_138963210.1 MarR family transcriptional regulator -
ELQ88_RS01565 264311..265555 + 1245 WP_138963212.1 sulfite oxidase -
ELQ88_RS01570 265530..265886 + 357 WP_138963214.1 cytochrome c -
ELQ88_RS01575 266420..266965 - 546 Protein_251 sprT domain-containing protein -
ELQ88_RS01580 267339..267791 - 453 WP_138963216.1 RES family NAD+ phosphorylase -
ELQ88_RS01585 267859..268230 - 372 WP_138963218.1 DUF2384 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..328214 328214


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Zinc finger, MqsA-type

(3-45)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10930.70 Da        Isoelectric Point: 7.2757

>T116510 WP_138963208.1 NZ_CP034782:c263516-263220 [Pseudomonas sp. MPC6]
MEKRTPHCKLSAVKALIEVGKVRTTQAARVGANELVLEFSQMLAVVTALTPADFYKSMPTHADHTVWQDVYRPNTQAGDV
YLKLTVIDDVLIVSFKEL

Download         Length: 297 bp

>T116510 NZ_CP034782:c263516-263220 [Pseudomonas sp. MPC6]
ATGGAAAAAAGAACACCCCACTGCAAGCTATCCGCCGTCAAAGCCTTGATCGAAGTGGGAAAGGTACGCACCACACAAGC
TGCGCGAGTTGGCGCGAATGAGTTGGTGCTTGAGTTTTCCCAGATGCTGGCCGTGGTGACGGCGCTTACGCCGGCGGATT
TCTACAAGAGCATGCCCACTCACGCCGATCACACGGTGTGGCAAGACGTTTACCGTCCAAACACGCAGGCGGGTGACGTG
TATCTGAAGCTGACGGTCATTGATGACGTGCTGATCGTGTCTTTTAAGGAGCTATAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14549.85 Da        Isoelectric Point: 7.6703

>AT116510 WP_138963206.1 NZ_CP034782:c263218-262817 [Pseudomonas sp. MPC6]
MKCPVCGAAELIHDTRDLPYTYKGETTVIAAVTGDFCPACAESVLGPVESDRVMREMRAFSKQVNAAIVDPGFITTVRKK
LALDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLKVLDRHPELLNEVRTT

Download         Length: 402 bp

>AT116510 NZ_CP034782:c263218-262817 [Pseudomonas sp. MPC6]
ATGAAATGTCCTGTTTGCGGCGCGGCTGAACTGATTCATGACACCCGCGACCTGCCCTACACCTACAAGGGCGAAACCAC
CGTCATTGCTGCGGTGACGGGGGACTTTTGTCCCGCCTGTGCCGAGTCTGTCTTGGGCCCAGTGGAGTCGGACCGCGTCA
TGCGCGAAATGCGTGCTTTCTCGAAGCAGGTCAACGCGGCCATTGTCGATCCGGGGTTTATAACCACCGTGCGCAAGAAG
CTTGCGCTCGATCAGCGTGAAGCGGCGGAAATTTTCGGCGGTGGCGTCAACGCGTTCTCGCGCTACGAAAATGGCAAGAC
CAAGCCGCCATTGGCGCTGGTGAAGCTGCTCAAGGTGCTTGATCGCCACCCGGAGCTGTTAAACGAAGTCAGGACGACAT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References