Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2803218..2803732 Replicon chromosome
Accession NZ_CP034767
Organism Devosia sp. 1566

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ELX51_RS13530 Protein ID WP_127754019.1
Coordinates 2803469..2803732 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ELX51_RS13525 Protein ID WP_127754018.1
Coordinates 2803218..2803472 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELX51_RS13510 2798357..2800849 - 2493 WP_206524625.1 acyl-CoA dehydrogenase -
ELX51_RS13515 2801061..2802782 + 1722 WP_127754016.1 long-chain fatty acid--CoA ligase -
ELX51_RS13520 2802779..2803168 + 390 WP_127754017.1 MerR family DNA-binding protein -
ELX51_RS13525 2803218..2803472 + 255 WP_127754018.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ELX51_RS13530 2803469..2803732 + 264 WP_127754019.1 Txe/YoeB family addiction module toxin Toxin
ELX51_RS13535 2803746..2804117 - 372 WP_206524626.1 UvrB/UvrC motif-containing protein -
ELX51_RS13540 2804129..2805706 - 1578 WP_127754021.1 cisplatin damage response ATP-dependent DNA ligase -
ELX51_RS13545 2805703..2806704 - 1002 WP_127754022.1 ligase-associated DNA damage response exonuclease -
ELX51_RS13550 2806738..2807439 - 702 WP_127754023.1 exopolysaccharide biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10617.01 Da        Isoelectric Point: 9.0358

>T116474 WP_127754019.1 NZ_CP034767:2803469-2803732 [Devosia sp. 1566]
MRLLFTEPGWDDYQYWQANDPDTLAKVNELIKDCRRSPFSGIGKPEPLKGNYKGWWSRRVTQEHRLVYRVEADVLWINQC
RFHYDRR

Download         Length: 264 bp

>T116474 NZ_CP034767:2803469-2803732 [Devosia sp. 1566]
ATGAGGCTCCTCTTCACCGAGCCGGGTTGGGATGACTATCAGTATTGGCAGGCCAATGATCCAGATACGCTGGCCAAGGT
CAACGAGCTGATCAAAGATTGCCGCCGCTCGCCATTTTCAGGCATCGGCAAACCCGAGCCCCTAAAGGGCAACTACAAGG
GCTGGTGGTCACGCCGCGTCACCCAGGAGCACCGACTGGTCTACCGCGTCGAGGCCGACGTCTTGTGGATCAACCAGTGC
CGCTTCCACTACGACCGGCGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9215.29 Da        Isoelectric Point: 4.4217

>AT116474 WP_127754018.1 NZ_CP034767:2803218-2803472 [Devosia sp. 1566]
MRAKSISDFRKNIAADIDAVVTDLEPLIVTRNGGKPPVVVMSLEEFESWKETIHLSSTQANADRLAQGNADFEAGRGIST
DWPE

Download         Length: 255 bp

>AT116474 NZ_CP034767:2803218-2803472 [Devosia sp. 1566]
ATGCGCGCCAAATCCATTTCCGATTTCCGCAAAAACATCGCCGCCGACATTGATGCAGTGGTGACCGACCTCGAGCCCTT
GATCGTCACCCGCAACGGCGGCAAGCCGCCGGTCGTGGTCATGTCACTGGAGGAATTTGAATCCTGGAAGGAAACTATTC
ACCTTTCCAGCACCCAGGCTAATGCCGATCGGCTGGCCCAGGGGAATGCCGATTTCGAAGCGGGCCGCGGCATCAGTACC
GACTGGCCTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References