Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2269046..2269707 Replicon chromosome
Accession NZ_CP034688
Organism Pseudomonas citronellolis strain WXP-4

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag ELR50_RS09825 Protein ID WP_269963809.1
Coordinates 2269360..2269707 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag ELR50_RS09820 Protein ID WP_269963808.1
Coordinates 2269046..2269363 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELR50_RS09795 (ELR50_09745) 2264076..2264840 - 765 WP_009620746.1 arginine/ornithine transport ATP-binding protein AotP -
ELR50_RS09800 (ELR50_09750) 2264856..2265968 - 1113 WP_269963806.1 M14 family metallopeptidase -
ELR50_RS09805 (ELR50_09755) 2265985..2266683 - 699 WP_269963807.1 ABC transporter permease -
ELR50_RS09810 (ELR50_09760) 2266697..2267386 - 690 WP_009620741.1 ABC transporter permease -
ELR50_RS09815 (ELR50_09765) 2267811..2268590 - 780 WP_009620740.1 ABC transporter substrate-binding protein -
ELR50_RS09820 (ELR50_09770) 2269046..2269363 - 318 WP_269963808.1 transcriptional regulator Antitoxin
ELR50_RS09825 (ELR50_09775) 2269360..2269707 - 348 WP_269963809.1 toxin Toxin
ELR50_RS09830 (ELR50_09780) 2269866..2271821 - 1956 WP_269963810.1 acetate--CoA ligase -
ELR50_RS09835 (ELR50_09785) 2271971..2273251 - 1281 WP_269963811.1 C4-dicarboxylate TRAP transporter large permease protein DctM -
ELR50_RS09840 (ELR50_09790) 2273248..2273880 - 633 WP_043267726.1 TRAP transporter small permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-92)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13475.48 Da        Isoelectric Point: 10.3571

>T116388 WP_269963809.1 NZ_CP034688:c2269707-2269360 [Pseudomonas citronellolis]
MKATFVELSPFERNRRHYLDDEAFRLFQQLLLTRPDAGDVIAGTGGLRKVRFGDPRRGKGRRGGLRVIYYCWLGGAQFWL
FTLYDKDEQDDLNERQRNQLAVLLQAELKLRGMVR

Download         Length: 348 bp

>T116388 NZ_CP034688:c2269707-2269360 [Pseudomonas citronellolis]
ATGAAGGCCACATTCGTTGAGCTATCCCCGTTCGAGCGTAATCGCCGTCATTACCTGGATGACGAGGCGTTTCGGTTGTT
CCAGCAGCTTCTGCTGACACGGCCCGACGCTGGCGACGTGATCGCCGGTACCGGCGGCCTGCGCAAGGTCCGTTTCGGTG
ATCCCAGGCGTGGCAAGGGAAGACGGGGAGGGTTGCGAGTGATCTATTACTGCTGGCTGGGGGGCGCCCAGTTCTGGTTG
TTCACCCTGTACGACAAGGATGAGCAGGATGATCTGAACGAGCGGCAGAGAAACCAGTTGGCCGTGCTGCTGCAGGCGGA
ATTGAAATTGAGAGGAATGGTGCGATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11835.61 Da        Isoelectric Point: 6.7289

>AT116388 WP_269963808.1 NZ_CP034688:c2269363-2269046 [Pseudomonas citronellolis]
MSKRDIFAELLEGFDDLAAERQGKITLRTHKVESAPLLPATGEEIAALRERLNMSQPVFARILHAAPATLKNWEQNRSRP
NDQATLLIRLLARHPETLDLITELA

Download         Length: 318 bp

>AT116388 NZ_CP034688:c2269363-2269046 [Pseudomonas citronellolis]
ATGAGCAAGCGTGACATCTTTGCCGAGTTGCTGGAGGGCTTCGACGATCTGGCGGCGGAGCGGCAGGGCAAGATCACCCT
GCGAACCCACAAGGTCGAATCGGCGCCACTGCTGCCTGCCACCGGGGAGGAGATAGCTGCCTTGCGCGAACGCCTGAACA
TGTCCCAGCCGGTCTTCGCCCGCATCCTCCATGCCGCACCGGCGACCTTGAAGAACTGGGAGCAGAATCGTTCGCGCCCC
AACGATCAGGCCACCTTGCTGATCCGTCTGTTGGCCAGGCACCCGGAAACCCTGGACTTGATTACCGAGTTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References