Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3670001..3670223 Replicon chromosome
Accession NZ_CP034658
Organism Escherichia coli strain ATCC 98082

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag EKH78_RS17765 Protein ID WP_000141634.1
Coordinates 3670001..3670108 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3670157..3670223 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKH78_RS17740 3665254..3665982 - 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -
EKH78_RS17745 3666018..3666206 - 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
EKH78_RS17750 3666479..3668050 + 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
EKH78_RS17755 3668047..3668238 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
EKH78_RS17760 3668235..3669914 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
EKH78_RS17765 3670001..3670108 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3670157..3670223 + 67 - - Antitoxin
EKH78_RS17770 3670584..3671855 + 1272 WP_001295225.1 aromatic amino acid transport family protein -
EKH78_RS17775 3671885..3672889 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
EKH78_RS17780 3672886..3673869 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
EKH78_RS17785 3673880..3674782 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T116332 WP_000141634.1 NZ_CP034658:c3670108-3670001 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T116332 NZ_CP034658:c3670108-3670001 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT116332 NZ_CP034658:3670157-3670223 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References