116189

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1822475..1822659 Replicon chromosome
Accession NZ_CP034486
Organism Staphylococcus aureus strain PMB 64-1

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EJN87_RS09535 Protein ID WP_000482647.1
Coordinates 1822552..1822659 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1822475..1822535 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJN87_RS09510 1817949..1818116 - 168 WP_001790576.1 hypothetical protein -
EJN87_RS09520 1818347..1820080 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
EJN87_RS09525 1820105..1821868 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 1822475..1822535 + 61 - - Antitoxin
EJN87_RS09535 1822552..1822659 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EJN87_RS09540 1822793..1823179 - 387 WP_000779360.1 flippase GtxA -
EJN87_RS09545 1823437..1824579 + 1143 WP_001176871.1 glycerate kinase -
EJN87_RS09550 1824639..1825298 + 660 WP_000831301.1 membrane protein -
EJN87_RS09555 1825480..1826691 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
EJN87_RS09560 1826814..1827287 - 474 WP_000456497.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T116189 WP_000482647.1 NZ_CP034486:c1822659-1822552 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T116189 NZ_CP034486:c1822659-1822552 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT116189 NZ_CP034486:1822475-1822535 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References