116186

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1539983..1540245 Replicon chromosome
Accession NZ_CP034486
Organism Staphylococcus aureus strain PMB 64-1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EJN87_RS08005 Protein ID WP_001802298.1
Coordinates 1540141..1540245 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1539983..1540146 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJN87_RS07985 1536232..1536897 - 666 WP_001024105.1 SDR family oxidoreductase -
EJN87_RS07990 1537049..1537369 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EJN87_RS07995 1537371..1538351 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
EJN87_RS08000 1538617..1539708 + 1092 WP_000495683.1 hypothetical protein -
- 1539983..1540146 + 164 - - Antitoxin
EJN87_RS08005 1540141..1540245 - 105 WP_001802298.1 hypothetical protein Toxin
EJN87_RS08015 1540925..1541083 + 159 WP_001792784.1 hypothetical protein -
EJN87_RS08025 1541742..1542599 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
EJN87_RS08030 1542667..1543449 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T116186 WP_001802298.1 NZ_CP034486:c1540245-1540141 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T116186 NZ_CP034486:c1540245-1540141 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT116186 NZ_CP034486:1539983-1540146 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References