Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 88910..89740 Replicon chromosome
Accession NZ_CP034481
Organism Rahnella aquatilis strain KM25

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag EJP79_RS00425 Protein ID WP_126124564.1
Coordinates 88910..89389 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0H3F4N7
Locus tag EJP79_RS00430 Protein ID WP_013573435.1
Coordinates 89396..89740 (-) Length 115 a.a.

Genomic Context

EJP79_RS00400EJP79_RS00405EJP79_RS00410EJP79_RS00415EJP79_RS00425EJP79_RS00430EJP79_RS00435EJP79_RS00440EJP79_RS00445EJP79_RS00450EJP79_RS00455
Location: 84195..85640 (1446 bp)
Type: Others
Protein ID: WP_112151980.1
Location: 85711..86169 (459 bp)
Type: Others
Protein ID: WP_013573431.1
Location: 86304..86726 (423 bp)
Type: Others
Protein ID: WP_013573432.1
Location: 86998..88677 (1680 bp)
Type: Others
Protein ID: WP_013573433.1
Location: 88910..89389 (480 bp)
Type: Toxin
Protein ID: WP_126124564.1
Location: 89396..89740 (345 bp)
Type: Antitoxin
Protein ID: WP_013573435.1
Location: 89822..89983 (162 bp)
Type: Others
Protein ID: WP_071882947.1
Location: 90124..91503 (1380 bp)
Type: Others
Protein ID: WP_013573436.1
Location: 91523..92305 (783 bp)
Type: Others
Protein ID: WP_014411455.1
Location: 92305..93171 (867 bp)
Type: Others
Protein ID: WP_014411456.1
Location: 93164..94099 (936 bp)
Type: Others
Protein ID: WP_112197519.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJP79_RS0040084195..85640+1446WP_112151980.1alpha/beta hydrolase-
EJP79_RS0040585711..86169+459WP_013573431.1MarR family transcriptional regulator-
EJP79_RS0041086304..86726+423WP_013573432.1organic hydroperoxide resistance protein-
EJP79_RS0041586998..88677+1680WP_013573433.1kdo(2)-lipid A phosphoethanolamine 7''-transferase-
EJP79_RS0042588910..89389-480WP_126124564.1type II toxin-antitoxin system YhaV family toxinToxin
EJP79_RS0043089396..89740-345WP_013573435.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
EJP79_RS0043589822..89983-162WP_071882947.1type II toxin-antitoxin system RelE/ParE family toxin-
EJP79_RS0044090124..91503-1380WP_013573436.1MmgE/PrpD family protein-
EJP79_RS0044591523..92305-783WP_014411455.1ABC transporter ATP-binding protein-
EJP79_RS0045092305..93171-867WP_014411456.1ABC transporter ATP-binding protein-
EJP79_RS0045593164..94099-936WP_112197519.1ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(13-148)

Antitoxin

SpoVT-AbrB domain

(15-53)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 18699.55 Da        Isoelectric Point: 9.9550

>T116119 WP_126124564.1 NZ_CP034481:c89389-88910 [Rahnella aquatilis]
MHNQAMEINGWTLLAHPLILQQIQALTDQVVLLRRKDPAGYKSKNATKRLAAINKLMFDVIPQDPARVEFRQGDTLGGEF
SHWFRAKFFQQYRLFFRYNLKSRIIIYAWVNDDKELRAYESKTDAYRMFRKMLKSGEPPDNWQALCEASGKIMAQEEQP

Download         Length: 480 bp

>T116119 NZ_CP034481:c89389-88910 [Rahnella aquatilis]
ATGCACAATCAGGCCATGGAGATTAACGGATGGACCCTTCTCGCTCATCCTCTGATCCTGCAACAAATACAGGCACTCAC
TGATCAGGTTGTTTTACTGCGCCGCAAAGATCCGGCGGGCTATAAAAGTAAAAATGCCACCAAACGGCTGGCTGCGATCA
ATAAGCTGATGTTTGACGTTATCCCGCAGGATCCGGCGCGTGTTGAATTCCGTCAGGGCGATACGTTAGGCGGGGAATTC
TCACACTGGTTCAGGGCAAAATTCTTCCAGCAGTACCGTTTGTTTTTCCGCTACAACCTGAAAAGCCGGATCATTATTTA
CGCCTGGGTGAATGATGATAAAGAATTACGCGCCTACGAAAGCAAAACAGACGCATACCGGATGTTTCGCAAGATGTTGA
AAAGCGGTGAACCGCCAGACAACTGGCAGGCACTTTGCGAGGCGTCAGGGAAAATAATGGCTCAGGAAGAACAGCCGTAG

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12701.48 Da        Isoelectric Point: 4.3324

>AT116119 WP_013573435.1 NZ_CP034481:c89740-89396 [Rahnella aquatilis]
MSASALWGIKFEAESKVTRRFQTTIPATIRKALNLTENDRIQYKILPDGQVVISRQLEEAEDPVISAFLGFVAKDMLNNP
ENMQPVTLSLHEKINVLTAGMAIDLESPLSDDDE

Download         Length: 345 bp

>AT116119 NZ_CP034481:c89740-89396 [Rahnella aquatilis]
ATGTCAGCCTCGGCACTATGGGGAATAAAATTCGAAGCCGAATCCAAAGTCACCCGCCGCTTCCAGACCACCATTCCGGC
CACTATCCGTAAGGCATTAAATCTCACCGAAAATGATCGGATCCAGTACAAGATTTTGCCAGACGGGCAGGTGGTTATTT
CGAGGCAACTCGAAGAAGCGGAAGACCCTGTTATCAGTGCTTTTCTCGGTTTTGTGGCAAAAGATATGCTCAATAACCCG
GAAAATATGCAGCCGGTAACATTATCCCTGCATGAAAAAATCAATGTACTGACCGCCGGGATGGCTATCGATCTTGAGAG
CCCGCTTTCTGACGATGACGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0H3F4N7

References