Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 2344116..2345446 | Replicon | chromosome |
Accession | NZ_CP034474 | ||
Organism | Pantoea agglomerans strain CFSAN047154 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | D1629_RS11175 | Protein ID | WP_111534011.1 |
Coordinates | 2344424..2345446 (+) | Length | 341 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | A0A8X8DQB2 |
Locus tag | D1629_RS11170 | Protein ID | WP_033758331.1 |
Coordinates | 2344116..2344427 (+) | Length | 104 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D1629_RS11145 | 2339574..2340956 | + | 1383 | WP_061901305.1 | FAD-binding protein | - |
D1629_RS11150 | 2340969..2341799 | + | 831 | WP_129062998.1 | glycosyltransferase family 8 protein | - |
D1629_RS11155 | 2341889..2343010 | - | 1122 | WP_129062999.1 | Gfo/Idh/MocA family oxidoreductase | - |
D1629_RS11165 | 2343787..2344131 | + | 345 | WP_111534010.1 | helix-turn-helix transcriptional regulator | - |
D1629_RS11170 | 2344116..2344427 | + | 312 | WP_033758331.1 | HipA N-terminal domain-containing protein | Antitoxin |
D1629_RS11175 | 2344424..2345446 | + | 1023 | WP_111534011.1 | HipA domain-containing protein | Toxin |
D1629_RS11180 | 2345572..2347749 | - | 2178 | WP_111534079.1 | catalase/peroxidase HPI | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 341 a.a. Molecular weight: 38638.27 Da Isoelectric Point: 7.0270
>T116112 WP_111534011.1 NZ_CP034474:2344424-2345446 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPEELAFVIKRYDRTASDNTRLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENDAGNAPGMNSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTKI
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPEELAFVIKRYDRTASDNTRLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENDAGNAPGMNSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTKI
Download Length: 1023 bp
>T116112 NZ_CP034474:2344424-2345446 [Pantoea agglomerans]
ATGAATTCAGAACGCTGCCTGATCACATTAAAACGGCTTAAAGAATCTGAGCTAAAAACCGGCTACTCAACAAAAGGCAT
CCGGCATCTGCTGGGTAGTCTGAATGTGGCTCTTAGCCTGCCGTTTACGCGCAGTCAGTTTATTCAGGAACTCCCTGAAC
GTCAGAAAGGCATGAGCATTTCAGGCTATCAACCCAAACTGTCGCTTCGCCTGGAAAAGGGAGAACTGGTGGTCGTCAGC
AATGATGGCACCTATATCCTGAAACCCTCTCCGGAAGAATATCCACACCTGGCAGAAAACGAGCATGCCACTATGTGCGT
TATGCAGCGTCTGAAATTTGACGTACCCCCGTTCGGGCTGATGCCATTCAGACACGATGAAAATCGGCCAGAAGAACTGG
CGTTTGTCATTAAAAGGTATGACCGGACAGCGTCAGATAACACGAGATTACATCAGGAACAGCTGGATGGCGCGATGGGT
CTCGGCGATAAATATGGCAGGATTGATAATCATAAAGCCATCAGTTATGAGAAAGCCGCTAAATTCCTGAATACCAGAGT
GAACAGCAGCTTAAAGAGTAAACGTGACCTCTTTTTGCGCATCGTGTATGCCTATGTGCTGGGAAACAATGATTTTCATC
TGCGCAATATCGGGATTATCCTGCCTCCGCAGGGTTCACCCTGGCTGGCCCCGGTTTATGACTTTATCAGCGTTGTGCCC
TACCCTGCAGCGTTTGGAGAGTATTTAGCTTTGCCCCTGCTGGAACGTGAAGAAAATGATGCAGGAAACGCACCGGGGAT
GAATTCAGAGTACGGAGAATATCTGGGTGCAGACTTTATCCTGCTTGCCCAGGGTATGGATATTAATCCGACACTGGCAC
GAAAATGGCTTTCCGAGGTGGTGAGTCATCATCAGCTTATTATCGATACTTATAATGAAAGTCATATGCCTGAATCGCAG
CGGGAAGCCGTACTTGACTACGTGGCCAGAAGAATCACGTTACTGGCAGTGACCAAAATTTAA
ATGAATTCAGAACGCTGCCTGATCACATTAAAACGGCTTAAAGAATCTGAGCTAAAAACCGGCTACTCAACAAAAGGCAT
CCGGCATCTGCTGGGTAGTCTGAATGTGGCTCTTAGCCTGCCGTTTACGCGCAGTCAGTTTATTCAGGAACTCCCTGAAC
GTCAGAAAGGCATGAGCATTTCAGGCTATCAACCCAAACTGTCGCTTCGCCTGGAAAAGGGAGAACTGGTGGTCGTCAGC
AATGATGGCACCTATATCCTGAAACCCTCTCCGGAAGAATATCCACACCTGGCAGAAAACGAGCATGCCACTATGTGCGT
TATGCAGCGTCTGAAATTTGACGTACCCCCGTTCGGGCTGATGCCATTCAGACACGATGAAAATCGGCCAGAAGAACTGG
CGTTTGTCATTAAAAGGTATGACCGGACAGCGTCAGATAACACGAGATTACATCAGGAACAGCTGGATGGCGCGATGGGT
CTCGGCGATAAATATGGCAGGATTGATAATCATAAAGCCATCAGTTATGAGAAAGCCGCTAAATTCCTGAATACCAGAGT
GAACAGCAGCTTAAAGAGTAAACGTGACCTCTTTTTGCGCATCGTGTATGCCTATGTGCTGGGAAACAATGATTTTCATC
TGCGCAATATCGGGATTATCCTGCCTCCGCAGGGTTCACCCTGGCTGGCCCCGGTTTATGACTTTATCAGCGTTGTGCCC
TACCCTGCAGCGTTTGGAGAGTATTTAGCTTTGCCCCTGCTGGAACGTGAAGAAAATGATGCAGGAAACGCACCGGGGAT
GAATTCAGAGTACGGAGAATATCTGGGTGCAGACTTTATCCTGCTTGCCCAGGGTATGGATATTAATCCGACACTGGCAC
GAAAATGGCTTTCCGAGGTGGTGAGTCATCATCAGCTTATTATCGATACTTATAATGAAAGTCATATGCCTGAATCGCAG
CGGGAAGCCGTACTTGACTACGTGGCCAGAAGAATCACGTTACTGGCAGTGACCAAAATTTAA
Antitoxin
Download Length: 104 a.a. Molecular weight: 11669.46 Da Isoelectric Point: 4.7953
>AT116112 WP_033758331.1 NZ_CP034474:2344116-2344427 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGQSGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS
MARKIEVWLYNTLAGTLSEGQSGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS
Download Length: 312 bp
>AT116112 NZ_CP034474:2344116-2344427 [Pantoea agglomerans]
ATGGCTCGAAAAATAGAGGTGTGGCTTTACAACACGCTGGCAGGAACGCTGAGTGAAGGGCAAAGCGGTTATACTTTCTG
CTACCTGCCCACTTATGTCGGCTGTGCGATATCTCTCAGCATGCCGGTAAGACCTGAGCCCTATTTAAGTGAAGAGCTAC
ATCCCTTCTTTAAAGGTTTAGCGCCGGAAGGCTGGTTGCGAAAACGCTATTCTGAAATTCAAAAAATTGATGATAAAGAT
CTGTTCGGCTTACTGATGGAAAATGGCAACGATTTGCTTGGGGCAGTCGTCTTTAAAGAGATAACATCATGA
ATGGCTCGAAAAATAGAGGTGTGGCTTTACAACACGCTGGCAGGAACGCTGAGTGAAGGGCAAAGCGGTTATACTTTCTG
CTACCTGCCCACTTATGTCGGCTGTGCGATATCTCTCAGCATGCCGGTAAGACCTGAGCCCTATTTAAGTGAAGAGCTAC
ATCCCTTCTTTAAAGGTTTAGCGCCGGAAGGCTGGTTGCGAAAACGCTATTCTGAAATTCAAAAAATTGATGATAAAGAT
CTGTTCGGCTTACTGATGGAAAATGGCAACGATTTGCTTGGGGCAGTCGTCTTTAAAGAGATAACATCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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