Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2571324..2572654 Replicon chromosome
Accession NZ_CP034469
Organism Pantoea agglomerans strain CFSAN047153

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag D1628_RS12185 Protein ID WP_111534011.1
Coordinates 2571632..2572654 (+) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID A0A8X8DQB2
Locus tag D1628_RS12180 Protein ID WP_033758331.1
Coordinates 2571324..2571635 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1628_RS12155 2566782..2568164 + 1383 WP_061901305.1 FAD-binding protein -
D1628_RS12160 2568177..2569007 + 831 WP_129062998.1 glycosyltransferase family 8 protein -
D1628_RS12165 2569097..2570218 - 1122 WP_129062999.1 Gfo/Idh/MocA family oxidoreductase -
D1628_RS12175 2570995..2571339 + 345 WP_111534010.1 helix-turn-helix transcriptional regulator -
D1628_RS12180 2571324..2571635 + 312 WP_033758331.1 HipA N-terminal domain-containing protein Antitoxin
D1628_RS12185 2571632..2572654 + 1023 WP_111534011.1 HipA domain-containing protein Toxin
D1628_RS12190 2572780..2574957 - 2178 WP_111534079.1 catalase/peroxidase HPI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38638.27 Da        Isoelectric Point: 7.0270

>T116100 WP_111534011.1 NZ_CP034469:2571632-2572654 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPEELAFVIKRYDRTASDNTRLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENDAGNAPGMNSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTKI

Download         Length: 1023 bp

>T116100 NZ_CP034469:2571632-2572654 [Pantoea agglomerans]
ATGAATTCAGAACGCTGCCTGATCACATTAAAACGGCTTAAAGAATCTGAGCTAAAAACCGGCTACTCAACAAAAGGCAT
CCGGCATCTGCTGGGTAGTCTGAATGTGGCTCTTAGCCTGCCGTTTACGCGCAGTCAGTTTATTCAGGAACTCCCTGAAC
GTCAGAAAGGCATGAGCATTTCAGGCTATCAACCCAAACTGTCGCTTCGCCTGGAAAAGGGAGAACTGGTGGTCGTCAGC
AATGATGGCACCTATATCCTGAAACCCTCTCCGGAAGAATATCCACACCTGGCAGAAAACGAGCATGCCACTATGTGCGT
TATGCAGCGTCTGAAATTTGACGTACCCCCGTTCGGGCTGATGCCATTCAGACACGATGAAAATCGGCCAGAAGAACTGG
CGTTTGTCATTAAAAGGTATGACCGGACAGCGTCAGATAACACGAGATTACATCAGGAACAGCTGGATGGCGCGATGGGT
CTCGGCGATAAATATGGCAGGATTGATAATCATAAAGCCATCAGTTATGAGAAAGCCGCTAAATTCCTGAATACCAGAGT
GAACAGCAGCTTAAAGAGTAAACGTGACCTCTTTTTGCGCATCGTGTATGCCTATGTGCTGGGAAACAATGATTTTCATC
TGCGCAATATCGGGATTATCCTGCCTCCGCAGGGTTCACCCTGGCTGGCCCCGGTTTATGACTTTATCAGCGTTGTGCCC
TACCCTGCAGCGTTTGGAGAGTATTTAGCTTTGCCCCTGCTGGAACGTGAAGAAAATGATGCAGGAAACGCACCGGGGAT
GAATTCAGAGTACGGAGAATATCTGGGTGCAGACTTTATCCTGCTTGCCCAGGGTATGGATATTAATCCGACACTGGCAC
GAAAATGGCTTTCCGAGGTGGTGAGTCATCATCAGCTTATTATCGATACTTATAATGAAAGTCATATGCCTGAATCGCAG
CGGGAAGCCGTACTTGACTACGTGGCCAGAAGAATCACGTTACTGGCAGTGACCAAAATTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11669.46 Da        Isoelectric Point: 4.7953

>AT116100 WP_033758331.1 NZ_CP034469:2571324-2571635 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGQSGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp

>AT116100 NZ_CP034469:2571324-2571635 [Pantoea agglomerans]
ATGGCTCGAAAAATAGAGGTGTGGCTTTACAACACGCTGGCAGGAACGCTGAGTGAAGGGCAAAGCGGTTATACTTTCTG
CTACCTGCCCACTTATGTCGGCTGTGCGATATCTCTCAGCATGCCGGTAAGACCTGAGCCCTATTTAAGTGAAGAGCTAC
ATCCCTTCTTTAAAGGTTTAGCGCCGGAAGGCTGGTTGCGAAAACGCTATTCTGAAATTCAAAAAATTGATGATAAAGAT
CTGTTCGGCTTACTGATGGAAAATGGCAACGATTTGCTTGGGGCAGTCGTCTTTAAAGAGATAACATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References