Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 357665..358317 | Replicon | chromosome |
Accession | NZ_CP034469 | ||
Organism | Pantoea agglomerans strain CFSAN047153 |
Toxin (Protein)
Gene name | higB | Uniprot ID | A0A8X8DRT2 |
Locus tag | D1628_RS01600 | Protein ID | WP_010672045.1 |
Coordinates | 357964..358317 (-) | Length | 118 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | A0A8X8DRN0 |
Locus tag | D1628_RS01595 | Protein ID | WP_010252120.1 |
Coordinates | 357665..357964 (-) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D1628_RS01575 | 353609..354574 | - | 966 | WP_033770846.1 | AraC family transcriptional regulator | - |
D1628_RS01580 | 354679..355866 | + | 1188 | WP_010252123.1 | MFS transporter | - |
D1628_RS01585 | 356079..356288 | + | 210 | WP_009092571.1 | DUF1471 domain-containing protein | - |
D1628_RS01590 | 356490..357542 | + | 1053 | WP_033770847.1 | YncE family protein | - |
D1628_RS01595 | 357665..357964 | - | 300 | WP_010252120.1 | XRE family transcriptional regulator | Antitoxin |
D1628_RS01600 | 357964..358317 | - | 354 | WP_010672045.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
D1628_RS01605 | 358552..359793 | - | 1242 | WP_033770848.1 | peptide antibiotic transporter SbmA | - |
D1628_RS01610 | 360070..360804 | + | 735 | WP_010672043.1 | gluconate 2-dehydrogenase subunit 3 family protein | - |
D1628_RS01615 | 360807..362591 | + | 1785 | WP_129062731.1 | GMC family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 118 a.a. Molecular weight: 13660.67 Da Isoelectric Point: 7.9792
>T116094 WP_010672045.1 NZ_CP034469:c358317-357964 [Pantoea agglomerans]
MWTVLLSPRFESWLSEQEEALQEKMLADLGKLKVYGPDLPRPYADTLKGSQYRNMKELRVQFSGKPIRAFYAFDPVRQAI
VLCAGDKSHDKRFYIRMIRIADDEFSAWLAEQEKGNN
MWTVLLSPRFESWLSEQEEALQEKMLADLGKLKVYGPDLPRPYADTLKGSQYRNMKELRVQFSGKPIRAFYAFDPVRQAI
VLCAGDKSHDKRFYIRMIRIADDEFSAWLAEQEKGNN
Download Length: 354 bp
>T116094 NZ_CP034469:c358317-357964 [Pantoea agglomerans]
ATGTGGACCGTACTCCTGAGCCCGCGCTTTGAAAGCTGGCTAAGTGAGCAGGAAGAAGCCCTGCAGGAAAAAATGTTAGC
GGATCTGGGAAAGTTAAAAGTATACGGCCCTGATTTGCCTCGCCCTTATGCTGATACTCTCAAGGGCTCGCAGTACAGGA
ATATGAAAGAACTCCGCGTACAGTTTTCAGGAAAGCCAATTCGGGCATTTTATGCATTTGACCCTGTCCGCCAGGCTATT
GTGTTATGTGCCGGAGATAAGAGTCATGACAAACGTTTTTATATCCGAATGATACGCATCGCTGACGATGAATTTTCAGC
CTGGCTGGCTGAACAGGAGAAGGGAAATAATTAA
ATGTGGACCGTACTCCTGAGCCCGCGCTTTGAAAGCTGGCTAAGTGAGCAGGAAGAAGCCCTGCAGGAAAAAATGTTAGC
GGATCTGGGAAAGTTAAAAGTATACGGCCCTGATTTGCCTCGCCCTTATGCTGATACTCTCAAGGGCTCGCAGTACAGGA
ATATGAAAGAACTCCGCGTACAGTTTTCAGGAAAGCCAATTCGGGCATTTTATGCATTTGACCCTGTCCGCCAGGCTATT
GTGTTATGTGCCGGAGATAAGAGTCATGACAAACGTTTTTATATCCGAATGATACGCATCGCTGACGATGAATTTTCAGC
CTGGCTGGCTGAACAGGAGAAGGGAAATAATTAA
Antitoxin
Download Length: 100 a.a. Molecular weight: 11116.99 Da Isoelectric Point: 6.3781
>AT116094 WP_010252120.1 NZ_CP034469:c357964-357665 [Pantoea agglomerans]
MRTLDDVIADFSPESQARIKKMSDEMILEVGLQMIREELQLSQKTLAEAMGVRQPAVAQIEQRGNEIKVATLKRYVEAMG
GKLSLDVELPTGKRVAFRI
MRTLDDVIADFSPESQARIKKMSDEMILEVGLQMIREELQLSQKTLAEAMGVRQPAVAQIEQRGNEIKVATLKRYVEAMG
GKLSLDVELPTGKRVAFRI
Download Length: 300 bp
>AT116094 NZ_CP034469:c357964-357665 [Pantoea agglomerans]
ATGAGAACCCTGGATGATGTTATCGCCGACTTCTCCCCTGAGAGTCAGGCGCGAATCAAAAAAATGTCTGATGAAATGAT
TCTGGAAGTCGGGCTTCAGATGATTCGCGAAGAGCTTCAGTTATCACAAAAGACGCTCGCCGAGGCCATGGGCGTGCGTC
AGCCTGCCGTTGCTCAGATTGAGCAACGCGGAAATGAGATTAAGGTTGCCACGCTGAAACGCTATGTCGAAGCAATGGGC
GGAAAACTCAGTCTTGATGTGGAACTTCCGACCGGAAAAAGAGTGGCCTTTCGCATCTGA
ATGAGAACCCTGGATGATGTTATCGCCGACTTCTCCCCTGAGAGTCAGGCGCGAATCAAAAAAATGTCTGATGAAATGAT
TCTGGAAGTCGGGCTTCAGATGATTCGCGAAGAGCTTCAGTTATCACAAAAGACGCTCGCCGAGGCCATGGGCGTGCGTC
AGCCTGCCGTTGCTCAGATTGAGCAACGCGGAAATGAGATTAAGGTTGCCACGCTGAAACGCTATGTCGAAGCAATGGGC
GGAAAACTCAGTCTTGATGTGGAACTTCCGACCGGAAAAAGAGTGGCCTTTCGCATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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