Detailed information of TA system TA116049

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2341079..2341261
• Replicon: chromosome
• Accession: NZ_CP034441
• Organism: Staphylococcus aureus strain PMB 81-4

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EJN89_RS12315
• Protein ID: WP_001801861.1
• Coordinates: 2341166..2341261 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2341079..2341138 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EJN89_RS12300	2340217..2340594	+	378	Protein_2250	DUF1433 domain-containing protein	-
EJN89_RS12305	2340788..2340964	+	177	Protein_2251	transposase	-
EJN89_RS12310	2340942..2341043	-	102	WP_001791893.1	hypothetical protein	-
-	2341079..2341138	+	60	-	-	Antitoxin
EJN89_RS12315	2341166..2341261	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
EJN89_RS12325	2341464..2341607	+	144	WP_001549059.1	transposase	-
EJN89_RS12335	2342211..2342594	+	384	WP_000070814.1	hypothetical protein	-
EJN89_RS12340	2342605..2342781	+	177	WP_000375477.1	hypothetical protein	-
EJN89_RS12350	2343155..2343712	+	558	Protein_2257	ImmA/IrrE family metallo-endopeptidase	-
EJN89_RS12355	2343910..2344482	-	573	WP_000414202.1	hypothetical protein	-
EJN89_RS12360	2344583..2344924	-	342	WP_000627541.1	DUF3969 family protein	-
EJN89_RS12365	2344965..2345591	-	627	WP_000669017.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2322559..2348149	25590

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T116049 WP_001801861.1 NZ_CP034441:c2341261-2341166 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T116049 NZ_CP034441:c2341261-2341166 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT116049 NZ_CP034441:2341079-2341138 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin