Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2007546..2007808 Replicon chromosome
Accession NZ_CP034441
Organism Staphylococcus aureus strain PMB 81-4

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EJN89_RS10265 Protein ID WP_001802298.1
Coordinates 2007546..2007650 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2007645..2007808 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJN89_RS10240 2004342..2005124 + 783 WP_000908178.1 ABC transporter ATP-binding protein -
EJN89_RS10245 2005192..2006049 + 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
EJN89_RS10255 2006708..2006866 - 159 WP_001792784.1 hypothetical protein -
EJN89_RS10265 2007546..2007650 + 105 WP_001802298.1 hypothetical protein Toxin
- 2007645..2007808 - 164 - - Antitoxin
EJN89_RS10270 2008083..2009174 - 1092 WP_000495683.1 hypothetical protein -
EJN89_RS10275 2009440..2010420 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
EJN89_RS10280 2010422..2010742 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EJN89_RS10285 2010894..2011559 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T116039 WP_001802298.1 NZ_CP034441:2007546-2007650 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T116039 NZ_CP034441:2007546-2007650 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT116039 NZ_CP034441:c2007808-2007645 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References