Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 5106040..5106820 Replicon chromosome
Accession NZ_CP034395
Organism Herbaspirillum seropedicae strain AU13965

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag EJD96_RS22960 Protein ID WP_139972523.1
Coordinates 5106524..5106820 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag EJD96_RS22955 Protein ID WP_139972522.1
Coordinates 5106040..5106522 (-) Length 161 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJD96_RS22935 5101205..5102767 - 1563 WP_041311350.1 MCP four helix bundle domain-containing protein -
EJD96_RS22940 5102923..5103759 - 837 WP_139972521.1 amidohydrolase family protein -
EJD96_RS22945 5103756..5104997 - 1242 WP_013236516.1 MFS transporter -
EJD96_RS22950 5105298..5106032 + 735 WP_069375272.1 GntR family transcriptional regulator -
EJD96_RS22955 5106040..5106522 - 483 WP_139972522.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EJD96_RS22960 5106524..5106820 - 297 WP_139972523.1 type II toxin-antitoxin system MqsR family toxin Toxin
EJD96_RS22965 5107254..5107931 + 678 WP_139972524.1 glutathione transferase -
EJD96_RS22970 5108035..5109291 - 1257 WP_013236521.1 MFS transporter -
EJD96_RS22975 5109753..5110475 + 723 WP_139972525.1 FadR family transcriptional regulator -
EJD96_RS22980 5110559..5111362 - 804 WP_069375278.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10919.74 Da        Isoelectric Point: 8.9102

>T115867 WP_139972523.1 NZ_CP034395:c5106820-5106524 [Herbaspirillum seropedicae]
MEKHTPHYKLAVVKSLLRQGQVRKTATALLGAAALGIDEMEMVAVVASLSSADFCKSMTTHADHRIWQDVYRPATRYGVL
YVKLTVLDDVLIVSFKEN

Download         Length: 297 bp

>T115867 NZ_CP034395:c5106820-5106524 [Herbaspirillum seropedicae]
ATGGAAAAACACACCCCACATTACAAGCTTGCAGTCGTGAAGTCCCTGCTCAGGCAGGGGCAGGTCCGCAAAACGGCGAC
CGCTCTTCTCGGTGCGGCGGCACTGGGCATCGATGAAATGGAAATGGTGGCCGTCGTCGCATCGTTGAGCAGCGCAGATT
TCTGCAAGAGCATGACCACCCATGCTGATCATCGTATCTGGCAAGACGTCTACCGGCCCGCCACCCGCTACGGTGTCCTC
TACGTCAAGTTGACCGTGCTTGATGATGTGCTGATCGTATCCTTCAAGGAGAACTGA

Antitoxin


Download         Length: 161 a.a.        Molecular weight: 17299.76 Da        Isoelectric Point: 8.0417

>AT115867 WP_139972522.1 NZ_CP034395:c5106522-5106040 [Herbaspirillum seropedicae]
MKCPHCGGAHLIRDTRDLPYAYKGETTVIAAVTGDYCPRCGECLPTTEEEARISAEALAFNKEINAGMIDPAEIISTREA
LQLGQREASLLFGGGINAFNRYEAGKIQPPRALVLLLRLLRKHPELLSELRADAGTSARGQAVHSVQEAGAGRLRSSSRK

Download         Length: 483 bp

>AT115867 NZ_CP034395:c5106522-5106040 [Herbaspirillum seropedicae]
ATGAAATGTCCCCATTGCGGAGGCGCGCACCTGATCCGCGACACGCGCGATCTGCCCTATGCCTACAAGGGTGAGACCAC
GGTCATTGCGGCGGTCACCGGCGACTATTGCCCGCGCTGCGGCGAGTGTCTGCCCACCACCGAAGAAGAAGCCAGGATCT
CGGCCGAGGCGCTGGCCTTCAATAAGGAAATCAACGCCGGGATGATCGATCCCGCCGAAATCATCTCCACCCGCGAGGCC
CTGCAACTGGGCCAGCGCGAGGCCAGCCTGCTGTTCGGCGGAGGGATCAATGCCTTCAATCGCTATGAGGCCGGCAAGAT
CCAGCCGCCGCGTGCGCTGGTGCTGTTGTTGCGCCTGTTGCGCAAGCACCCGGAGTTGCTCAGTGAACTGCGTGCCGACG
CCGGCACGAGCGCGCGTGGCCAGGCCGTCCATTCGGTCCAGGAAGCCGGCGCCGGCCGCTTGCGCTCCAGCTCGCGCAAG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References