Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2766674..2767381 Replicon chromosome
Accession NZ_CP034395
Organism Herbaspirillum seropedicae strain AU13965

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag EJD96_RS12475 Protein ID WP_139971118.1
Coordinates 2767079..2767381 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag EJD96_RS12470 Protein ID WP_013234491.1
Coordinates 2766674..2767075 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJD96_RS12445 2761771..2762964 + 1194 WP_139971115.1 NO-inducible flavohemoprotein -
EJD96_RS12450 2763014..2763421 + 408 WP_041311897.1 hemerythrin domain-containing protein -
EJD96_RS12455 2763598..2763954 + 357 WP_139971116.1 hypothetical protein -
EJD96_RS12460 2763955..2764947 - 993 WP_139971117.1 2-hydroxyacid dehydrogenase -
EJD96_RS12465 2765286..2766572 + 1287 WP_069374077.1 MFS transporter -
EJD96_RS12470 2766674..2767075 - 402 WP_013234491.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EJD96_RS12475 2767079..2767381 - 303 WP_139971118.1 type II toxin-antitoxin system MqsR family toxin Toxin
EJD96_RS12480 2767720..2769948 + 2229 WP_139971119.1 NADP-dependent isocitrate dehydrogenase -
EJD96_RS12485 2770233..2771102 - 870 WP_139971120.1 ethanolamine ammonia-lyase subunit EutC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-99)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11076.99 Da        Isoelectric Point: 9.2564

>T115865 WP_139971118.1 NZ_CP034395:c2767381-2767079 [Herbaspirillum seropedicae]
MEKHTAHCKLPVVRKLIEAGKVKATATAFQGARACGIGDLDGICAVILGLRPRDFHKSMTTHADHRVWQDVYHARLHNGM
VAYLKLSVVDDVLVVSFKEL

Download         Length: 303 bp

>T115865 NZ_CP034395:c2767381-2767079 [Herbaspirillum seropedicae]
ATGGAGAAGCATACCGCCCACTGCAAGCTGCCCGTGGTCAGGAAACTGATCGAAGCAGGGAAGGTAAAAGCGACCGCTAC
CGCCTTCCAGGGCGCGAGGGCGTGCGGCATCGGGGACCTTGATGGCATCTGCGCGGTGATCCTGGGGCTCAGGCCCCGTG
ACTTCCATAAAAGCATGACCACCCACGCAGACCATCGGGTCTGGCAGGATGTCTACCACGCCAGGCTGCACAATGGCATG
GTGGCTTATCTCAAGCTCAGCGTGGTCGACGACGTGCTGGTGGTTTCCTTCAAGGAGCTGTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14957.10 Da        Isoelectric Point: 7.1658

>AT115865 WP_013234491.1 NZ_CP034395:c2767075-2766674 [Herbaspirillum seropedicae]
MKCPCCGAAELVHETRDLPYTYKGESTLIAQVKGDFCPACGEVLLDREHGDRYSELIGQFQRKVNAAYVDPAYIARVRRK
LDLDQREAGELFGGGVNAFSRYENGKTKPPLSLVKLFRLLDRHPDLLDEIRAA

Download         Length: 402 bp

>AT115865 NZ_CP034395:c2767075-2766674 [Herbaspirillum seropedicae]
ATGAAATGTCCTTGCTGCGGCGCAGCCGAACTGGTCCACGAAACACGTGACCTGCCCTATACCTACAAGGGCGAAAGCAC
CCTCATTGCACAGGTGAAGGGGGACTTCTGTCCTGCCTGCGGCGAAGTCCTGCTCGATCGGGAGCATGGCGACCGCTACA
GCGAACTGATCGGGCAATTCCAGCGCAAGGTGAATGCGGCCTACGTGGACCCCGCCTACATAGCCCGGGTCCGGCGCAAG
CTCGATCTCGACCAGCGCGAGGCAGGCGAGCTCTTCGGCGGCGGCGTCAATGCCTTTTCCCGTTACGAGAACGGCAAGAC
CAAGCCGCCGCTCTCACTGGTCAAGCTGTTCAGGTTGCTGGACCGGCATCCCGACCTGCTGGATGAAATCCGCGCCGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References