Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 784397..785052 Replicon chromosome
Accession NZ_CP034363
Organism Pantoea sp. CCBC3-3-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EHV07_RS03535 Protein ID WP_147195125.1
Coordinates 784714..785052 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EHV07_RS03530 Protein ID WP_147195124.1
Coordinates 784397..784717 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHV07_RS03520 780200..783424 + 3225 WP_147195122.1 carbamoyl-phosphate synthase large subunit -
EHV07_RS03525 783629..784363 + 735 WP_147195123.1 phosphatase PAP2 family protein -
EHV07_RS03530 784397..784717 - 321 WP_147195124.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EHV07_RS03535 784714..785052 - 339 WP_147195125.1 toxin Toxin
EHV07_RS03540 785333..785947 - 615 WP_147195127.1 LysE family translocator -
EHV07_RS03545 786141..786620 + 480 WP_147200514.1 type 3 dihydrofolate reductase -
EHV07_RS03550 786653..787483 - 831 WP_147195129.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH -
EHV07_RS03555 787538..787915 - 378 WP_147195131.1 Co2+/Mg2+ efflux protein ApaG -
EHV07_RS03560 787919..788746 - 828 WP_147195134.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
EHV07_RS03565 788739..789731 - 993 WP_147195138.1 4-hydroxythreonine-4-phosphate dehydrogenase PdxA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(45-88)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13021.95 Da        Isoelectric Point: 6.7166

>T115783 WP_147195125.1 NZ_CP034363:c785052-784714 [Pantoea sp. CCBC3-3-1]
VDAIFVELPPFARHRADYLSDEAFISLQNLLMLSPWCDDVIQHTGGLRKVRLGDEDRQKGKRTGLRVIYYWWQENAQFLL
FTLYSKGEMGDLTVSQKSMLRQLLDYHMAGTP

Download         Length: 339 bp

>T115783 NZ_CP034363:c785052-784714 [Pantoea sp. CCBC3-3-1]
GTGGATGCTATCTTTGTCGAACTTCCGCCATTCGCACGCCATCGTGCGGATTATCTCTCCGATGAGGCGTTTATCAGCCT
GCAAAATCTCTTAATGCTTTCGCCATGGTGTGATGACGTTATCCAACACACGGGCGGATTGCGTAAAGTCAGGTTAGGCG
ATGAGGACCGCCAAAAAGGGAAGCGTACAGGCCTGCGGGTGATTTATTACTGGTGGCAGGAAAACGCCCAGTTCCTCCTT
TTTACGCTTTACAGTAAGGGAGAAATGGGCGATCTCACCGTCTCGCAGAAAAGCATGCTGCGTCAGTTGCTTGATTATCA
TATGGCAGGAACACCATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12205.19 Da        Isoelectric Point: 10.2575

>AT115783 WP_147195124.1 NZ_CP034363:c784717-784397 [Pantoea sp. CCBC3-3-1]
MKKRQLFNELVEGMDAWGEMNAGKKTLKTHRLSVEREIVLPSSELRQIRESLQLSQALFAQYLHTGLTTYQNWEQGRAKP
NKQAILLIRMVEKDPQLLQTLAGLSL

Download         Length: 321 bp

>AT115783 NZ_CP034363:c784717-784397 [Pantoea sp. CCBC3-3-1]
ATGAAAAAACGACAGTTGTTCAATGAGCTGGTTGAAGGGATGGATGCCTGGGGAGAGATGAATGCGGGCAAAAAAACGCT
GAAAACTCACCGGCTGAGCGTTGAACGCGAAATTGTGTTGCCCTCGTCTGAGCTACGGCAGATCAGGGAGTCGCTACAGC
TTTCGCAGGCGCTGTTTGCCCAGTACTTACATACCGGGCTGACCACCTATCAAAACTGGGAGCAGGGTCGTGCTAAACCC
AACAAGCAGGCGATTCTGCTTATCCGCATGGTTGAAAAAGATCCTCAGCTGCTGCAAACCCTTGCCGGATTGTCGCTGTA
G

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References