Detailed information of TA system TA115768

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2388638..2388822
• Replicon: chromosome
• Accession: NZ_CP034349
• Organism: Staphylococcus aureus strain 80wphwpl

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: C6567_RS12120
• Protein ID: WP_000482648.1
• Coordinates: 2388715..2388822 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2388638..2388698 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C6567_RS12095	2384148..2384315	-	168	Protein_2245	hypothetical protein	-
C6567_RS12105	2384546..2386279	-	1734	WP_000486505.1	ABC transporter ATP-binding protein/permease	-
C6567_RS12110	2386304..2388067	-	1764	WP_001064829.1	ABC transporter ATP-binding protein/permease	-
-	2388638..2388698	+	61	-	-	Antitoxin
C6567_RS12120	2388715..2388822	-	108	WP_000482648.1	type I toxin-antitoxin system Fst family toxin	Toxin
C6567_RS12125	2388956..2389342	-	387	WP_000779351.1	flippase GtxA	-
C6567_RS12130	2389610..2390752	+	1143	WP_001176855.1	glycerate kinase	-
C6567_RS12135	2390812..2391471	+	660	WP_000831298.1	membrane protein	-
C6567_RS12140	2391653..2392864	+	1212	WP_001191919.1	multidrug effflux MFS transporter	-
C6567_RS12145	2392987..2393460	-	474	WP_000456496.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4026.79 Da
• Isoelectric Point: 10.4935

>T115768 WP_000482648.1 NZ_CP034349:c2388822-2388715 [Staphylococcus aureus]
MFNLLIEIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T115768 NZ_CP034349:c2388822-2388715 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGAAATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT115768 NZ_CP034349:2388638-2388698 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin