Detailed information of TA system TA115766

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-sprA1AS/-
• Location: 2103622..2103819
• Replicon: chromosome
• Accession: NZ_CP034349
• Organism: Staphylococcus aureus strain 80wphwpl

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: C6567_RS10565
• Protein ID: WP_073392962.1
• Coordinates: 2103715..2103819 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2103622..2103660 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C6567_RS10545	2099797..2100462	-	666	WP_001024099.1	SDR family oxidoreductase	-
C6567_RS10550	2100614..2100934	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
C6567_RS10555	2100936..2101916	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
C6567_RS10560	2102182..2103273	+	1092	WP_000495684.1	hypothetical protein	-
-	2103622..2103660	+	39	-	-	Antitoxin
C6567_RS10565	2103715..2103819	-	105	WP_073392962.1	hypothetical protein	Toxin
C6567_RS10575	2104499..2104657	+	159	WP_001792784.1	hypothetical protein	-
C6567_RS10585	2105316..2106173	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
C6567_RS10590	2106241..2107023	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T115766 WP_073392962.1 NZ_CP034349:c2103819-2103715 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T115766 NZ_CP034349:c2103819-2103715 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 39 bp

>AT115766 NZ_CP034349:2103622-2103660 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin