Detailed information of TA system TA115760

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1812882..1813062
• Replicon: chromosome
• Accession: NZ_CP034349
• Organism: Staphylococcus aureus strain 80wphwpl

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: C6567_RS08870
• Protein ID: WP_001801861.1
• Coordinates: 1812882..1812977 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1813005..1813062 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C6567_RS08835	1808026..1808652	+	627	WP_000669038.1	hypothetical protein	-
C6567_RS08840	1808693..1809037	+	345	WP_000627550.1	DUF3969 family protein	-
C6567_RS08845	1809135..1809707	+	573	WP_000414222.1	hypothetical protein	-
C6567_RS08850	1809856..1811223	-	1368	WP_001093574.1	FRG domain-containing protein	-
C6567_RS08855	1811223..1811792	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
C6567_RS08860	1811985..1812431	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
C6567_RS08870	1812882..1812977	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1813005..1813062	-	58	-	-	Antitoxin
C6567_RS08875	1813100..1813201	+	102	WP_001791232.1	hypothetical protein	-
C6567_RS08880	1813376..1813819	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
C6567_RS08885	1813819..1814262	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
C6567_RS08890	1814262..1814704	-	443	Protein_1682	DUF1433 domain-containing protein	-
C6567_RS08895	1815229..1817649	+	2421	WP_000182551.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T115760 WP_001801861.1 NZ_CP034349:1812882-1812977 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T115760 NZ_CP034349:1812882-1812977 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT115760 NZ_CP034349:c1813062-1813005 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin