Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-chpS/PRK09812-MazE
Location 5113738..5114336 Replicon chromosome
Accession NZ_CP034338
Organism Pseudomonas entomophila strain 1257

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag EJA05_RS23850 Protein ID WP_125860317.1
Coordinates 5113738..5114085 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag EJA05_RS23855 Protein ID WP_190306022.1
Coordinates 5114082..5114336 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJA05_RS23825 5109227..5109712 - 486 WP_125465500.1 peptidylprolyl isomerase -
EJA05_RS23830 5109711..5110013 + 303 WP_125860315.1 DUF3565 domain-containing protein -
EJA05_RS23835 5110046..5112136 + 2091 WP_110994811.1 phosphate acetyltransferase -
EJA05_RS23840 5112259..5112978 - 720 WP_125465502.1 OmpA family protein -
EJA05_RS23845 5113074..5113718 - 645 WP_110994809.1 MBL fold metallo-hydrolase -
EJA05_RS23850 5113738..5114085 - 348 WP_125860317.1 type II toxin-antitoxin system ChpB family toxin Toxin
EJA05_RS23855 5114082..5114336 - 255 WP_190306022.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EJA05_RS23860 5114507..5115199 - 693 WP_125465505.1 HAMP domain-containing histidine kinase -
EJA05_RS23865 5115196..5116803 - 1608 WP_125860321.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-113)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12292.11 Da        Isoelectric Point: 9.4897

>T115756 WP_125860317.1 NZ_CP034338:c5114085-5113738 [Pseudomonas entomophila]
MKRGRFDRGDIVRINLDPTVGREQQGASRPALVLTPAMFNTSGLAVIVPISQGGDFSRHAGFAVTLSGAGTQTQGVMLCN
QLRTVDLEARGAKRIESVPEAVILDALARVQTLFD

Download         Length: 348 bp

>T115756 NZ_CP034338:c5114085-5113738 [Pseudomonas entomophila]
TTGAAGCGGGGCAGGTTCGACAGGGGGGATATCGTCCGGATCAACCTGGACCCCACCGTCGGTAGAGAACAGCAAGGTGC
TTCGCGCCCTGCGCTGGTGTTGACGCCCGCCATGTTCAATACCTCTGGGCTCGCGGTGATCGTGCCGATTTCACAAGGTG
GGGATTTCTCCCGGCACGCAGGTTTTGCAGTTACCCTGAGCGGCGCCGGTACCCAGACGCAAGGTGTGATGCTGTGCAAT
CAGCTACGCACGGTAGACCTTGAAGCGAGGGGTGCCAAGCGCATCGAATCCGTTCCCGAAGCCGTGATCCTGGACGCGCT
GGCGCGTGTTCAAACCCTCTTCGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9320.80 Da        Isoelectric Point: 5.7808

>AT115756 WP_190306022.1 NZ_CP034338:c5114336-5114082 [Pseudomonas entomophila]
MQIKIQQWGNSAAIRLPATVLKQMHLSVGSTLSLDTSGETLVLKPVRSKPEYRLEELMAQCDLTAPEPADMADWNAMRPV
GREV

Download         Length: 255 bp

>AT115756 NZ_CP034338:c5114336-5114082 [Pseudomonas entomophila]
ATGCAGATCAAGATTCAGCAATGGGGCAACAGCGCAGCGATTCGTCTGCCGGCGACGGTCCTCAAGCAAATGCACCTGAG
CGTGGGGTCGACCCTGAGCCTGGATACTTCCGGCGAGACCCTGGTGCTCAAACCTGTCAGATCGAAGCCCGAGTACCGGC
TCGAAGAGTTGATGGCGCAATGTGACCTGACAGCCCCGGAACCCGCAGACATGGCTGACTGGAACGCAATGCGTCCGGTG
GGGCGTGAGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References