Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4146185..4146885 Replicon chromosome
Accession NZ_CP034338
Organism Pseudomonas entomophila strain 1257

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag EJA05_RS19485 Protein ID WP_125859469.1
Coordinates 4146589..4146885 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag EJA05_RS19480 Protein ID WP_125859468.1
Coordinates 4146185..4146586 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJA05_RS19460 4141329..4142150 - 822 WP_125859465.1 transporter substrate-binding domain-containing protein -
EJA05_RS19465 4142235..4143164 - 930 WP_125859466.1 FAD-binding protein -
EJA05_RS19470 4143165..4143914 - 750 WP_125464898.1 electron transfer flavoprotein subunit beta/FixA family protein -
EJA05_RS19475 4144443..4146125 + 1683 WP_125859467.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
EJA05_RS19480 4146185..4146586 - 402 WP_125859468.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EJA05_RS19485 4146589..4146885 - 297 WP_125859469.1 type II toxin-antitoxin system MqsR family toxin Toxin
EJA05_RS19490 4146980..4148305 - 1326 WP_125859470.1 MFS transporter -
EJA05_RS19495 4148367..4148852 - 486 WP_125464903.1 histidine kinase -
EJA05_RS19500 4149021..4149497 - 477 WP_125464904.1 sigma-70 family RNA polymerase sigma factor -
EJA05_RS19505 4149716..4150891 + 1176 WP_125859471.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11138.08 Da        Isoelectric Point: 8.4626

>T115754 WP_125859469.1 NZ_CP034338:c4146885-4146589 [Pseudomonas entomophila]
MEKRVPHCPLDRVKALLAVKRISPTFAALRGARSLGLDYPGMLDVISSLERTDFYKSMTCYTEHGVWQDIYRPLTAVGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T115754 NZ_CP034338:c4146885-4146589 [Pseudomonas entomophila]
ATGGAAAAGAGAGTGCCTCACTGTCCACTTGATCGGGTAAAAGCGCTGCTTGCTGTAAAGCGGATCAGTCCGACCTTCGC
TGCATTAAGAGGTGCCAGGTCTCTGGGCCTGGATTACCCAGGAATGCTCGATGTGATCAGCAGTCTGGAACGCACTGATT
TTTACAAAAGCATGACCTGCTATACGGAACACGGCGTCTGGCAGGACATATACCGTCCGCTCACGGCAGTCGGCTACGTT
TACCTGAAACTGTCAGTGGTCGATGACGTGCTCATCGTGTCCTTCAAGGAGCTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14632.61 Da        Isoelectric Point: 4.9775

>AT115754 WP_125859468.1 NZ_CP034338:c4146586-4146185 [Pseudomonas entomophila]
MRCPICGGAELAPDIQDMPYRYKGESTLIQGVSGDYCSACGEAVLSHDEAMRVSEQMSAFERRVNAAAVDPAFISAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALIKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT115754 NZ_CP034338:c4146586-4146185 [Pseudomonas entomophila]
ATGAGATGCCCGATCTGCGGTGGCGCGGAGCTTGCGCCAGATATTCAGGACATGCCCTACCGCTACAAAGGAGAGTCGAC
TCTGATCCAGGGCGTCAGCGGCGACTACTGCTCTGCCTGTGGTGAGGCGGTCCTGAGCCACGACGAAGCCATGCGTGTCA
GTGAACAGATGTCGGCCTTTGAGCGTCGGGTCAATGCGGCCGCGGTTGATCCAGCTTTCATCAGCGCCGTGCGCAAGAAA
TTCGACCTGGACCAGCGCGAGGCGGGTGAGATTTTCGGTGGTGGGGTCAACGCCTTTTCCCGCTACGAAAATGGTAAAAC
CACGCCGCCAGTGGCGTTGATCAAGCTGTTCAAGCTGCTCGACCGCCACCCCGAGCTGTTCGAGGAAGTCAGGACCGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References