Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1161427..1162031 Replicon chromosome
Accession NZ_CP034338
Organism Pseudomonas entomophila strain 1257

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag EJA05_RS05510 Protein ID WP_125462793.1
Coordinates 1161711..1162031 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag EJA05_RS05505 Protein ID WP_125462792.1
Coordinates 1161427..1161714 (-) Length 96 a.a.

Genomic Context

EJA05_RS05480EJA05_RS05485EJA05_RS05495EJA05_RS05500EJA05_RS05505EJA05_RS05510EJA05_RS05515EJA05_RS05525EJA05_RS05530EJA05_RS05535
Location: 1157405..1158013 (609 bp)
Type: Others
Protein ID: WP_125462787.1
Location: 1158113..1159333 (1221 bp)
Type: Others
Protein ID: WP_125857590.1
Location: 1159777..1160286 (510 bp)
Type: Others
Protein ID: WP_125857591.1
Location: 1160309..1161319 (1011 bp)
Type: Others
Protein ID: WP_125857592.1
Location: 1161427..1161714 (288 bp)
Type: Antitoxin
Protein ID: WP_125462792.1
Location: 1161711..1162031 (321 bp)
Type: Toxin
Protein ID: WP_125462793.1
Location: 1162163..1163863 (1701 bp)
Type: Others
Protein ID: WP_125857593.1
Location: 1164255..1165139 (885 bp)
Type: Others
Protein ID: WP_125462795.1
Location: 1165587..1166279 (693 bp)
Type: Others
Protein ID: WP_125857594.1
Location: 1166311..1166532 (222 bp)
Type: Others
Protein ID: WP_125462797.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJA05_RS054801157405..1158013+609WP_125462787.1hypothetical protein-
EJA05_RS054851158113..1159333+1221WP_125857590.1SAM-dependent methyltransferase-
EJA05_RS054951159777..1160286+510WP_125857591.1DNA-binding protein-
EJA05_RS055001160309..1161319-1011WP_125857592.1DUF4917 family protein-
EJA05_RS055051161427..1161714-288WP_125462792.1helix-turn-helix domain-containing proteinAntitoxin
EJA05_RS055101161711..1162031-321WP_125462793.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EJA05_RS055151162163..1163863-1701WP_125857593.1SulP family inorganic anion transporter-
EJA05_RS055251164255..1165139-885WP_125462795.1alpha/beta hydrolase-
EJA05_RS055301165587..1166279-693WP_125857594.116S rRNA pseudouridine(516) synthase-
EJA05_RS055351166311..1166532-222WP_125462797.1cysteine-rich CWC family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-87)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12091.90 Da        Isoelectric Point: 10.1563

>T115751 WP_125462793.1 NZ_CP034338:c1162031-1161711 [Pseudomonas entomophila]
MLFTETAVFTKRAKELLDDETYRLLQVRLLISPDAGDVIEGTGGLRKIRAPANGHGKRGGARVIYYHFTARSHITLLYIF
AKNEQTELSAEQRKALKSVIENWRYP

Download         Length: 321 bp

>T115751 NZ_CP034338:c1162031-1161711 [Pseudomonas entomophila]
ATGCTTTTTACCGAAACCGCTGTCTTTACCAAGCGCGCAAAAGAGCTGCTCGACGACGAAACCTACAGGTTGTTGCAGGT
TCGTCTTTTGATATCCCCCGATGCAGGGGATGTCATCGAAGGGACCGGCGGCCTGCGCAAAATCCGCGCCCCAGCGAACG
GCCACGGCAAGCGAGGCGGCGCCAGAGTCATCTACTACCACTTCACGGCAAGGTCACATATCACCTTGCTCTACATCTTT
GCGAAGAACGAACAAACGGAGCTATCCGCCGAACAGCGCAAGGCTTTGAAGTCCGTCATCGAAAACTGGAGATACCCATG
A

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10949.55 Da        Isoelectric Point: 6.7284

>AT115751 WP_125462792.1 NZ_CP034338:c1161714-1161427 [Pseudomonas entomophila]
MSRLFDELMESVVEMDEIIQGKRQPSRQFEIDALQVREIRKATGLSQVRFAEMIDVQVATLRNWEQGRREPTGPAKALLR
AIHNDPDHVLKALSH

Download         Length: 288 bp

>AT115751 NZ_CP034338:c1161714-1161427 [Pseudomonas entomophila]
ATGAGCCGCCTCTTCGACGAACTGATGGAAAGCGTTGTAGAAATGGATGAAATCATCCAGGGCAAACGCCAACCCTCGCG
CCAGTTCGAAATCGACGCCCTTCAAGTCCGGGAAATCCGTAAGGCCACCGGTTTGTCACAGGTACGTTTCGCCGAGATGA
TCGATGTGCAAGTCGCTACGCTGCGTAACTGGGAACAGGGGCGCCGGGAGCCCACGGGGCCTGCCAAGGCGCTGCTGCGG
GCCATCCACAACGACCCTGATCACGTGCTCAAGGCCTTGTCGCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References