Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-chpS/PRK09812-MazE
Location 4752309..4752907 Replicon chromosome
Accession NZ_CP034337
Organism Pseudomonas entomophila strain 2014

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag EI693_RS22030 Protein ID WP_125465503.1
Coordinates 4752309..4752656 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag EI693_RS22035 Protein ID WP_189654498.1
Coordinates 4752653..4752907 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI693_RS22005 4747837..4748322 - 486 WP_125465500.1 peptidylprolyl isomerase -
EI693_RS22010 4748321..4748623 + 303 WP_125466247.1 DUF3565 domain-containing protein -
EI693_RS22015 4748656..4750746 + 2091 WP_125465501.1 phosphate acetyltransferase -
EI693_RS22020 4750830..4751549 - 720 WP_125465502.1 OmpA family protein -
EI693_RS22025 4751645..4752289 - 645 WP_110994809.1 MBL fold metallo-hydrolase -
EI693_RS22030 4752309..4752656 - 348 WP_125465503.1 type II toxin-antitoxin system ChpB family toxin Toxin
EI693_RS22035 4752653..4752907 - 255 WP_189654498.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EI693_RS22040 4753078..4753770 - 693 WP_125465505.1 HAMP domain-containing histidine kinase -
EI693_RS22045 4753767..4755374 - 1608 WP_125465506.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-114)

Antitoxin

SpoVT-AbrB domain

(6-50)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12364.17 Da        Isoelectric Point: 8.0308

>T115747 WP_125465503.1 NZ_CP034337:c4752656-4752309 [Pseudomonas entomophila]
MKRARFDRGDIVRINLDPTVDREQQGASRPALVLTPAMFNTSGLAVIVPISQGGDFSRHAGFAVTLSGAGTQTQGVMLCN
QLRTVDLEARGAKRIESVPEAVILDALARVQTLFD

Download         Length: 348 bp

>T115747 NZ_CP034337:c4752656-4752309 [Pseudomonas entomophila]
TTGAAGCGGGCCAGGTTCGACAGAGGGGATATCGTCCGGATCAACCTGGACCCCACCGTCGATAGAGAACAGCAAGGTGC
TTCGCGCCCTGCGCTGGTGTTGACGCCCGCCATGTTCAATACCTCTGGTCTCGCGGTGATCGTGCCGATTTCACAAGGTG
GGGATTTCTCCCGGCACGCAGGTTTTGCAGTTACCCTGAGCGGCGCCGGTACCCAGACGCAAGGTGTGATGCTGTGCAAT
CAGCTACGCACGGTAGACCTTGAAGCGAGGGGCGCCAAGCGCATCGAATCCGTTCCCGAAGCCGTGATCCTGGACGCGCT
GGCGCGTGTTCAAACCCTCTTCGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9292.75 Da        Isoelectric Point: 5.7808

>AT115747 WP_189654498.1 NZ_CP034337:c4752907-4752653 [Pseudomonas entomophila]
MQIKIQQWGNSAAIRLPATVLKQMHLSVGSTLSLDTSGETLVLKPVRSKPEYRLEELMAQCDLTAPEPADMADWNAMRPV
GREA

Download         Length: 255 bp

>AT115747 NZ_CP034337:c4752907-4752653 [Pseudomonas entomophila]
ATGCAGATCAAGATTCAGCAATGGGGCAACAGCGCAGCGATTCGTCTGCCGGCGACGGTCCTCAAGCAAATGCACCTGAG
CGTGGGGTCGACCCTGAGCCTGGATACTTCCGGCGAGACCTTGGTGCTCAAACCGGTCAGGTCGAAGCCCGAGTACCGGC
TGGAAGAGCTGATGGCGCAATGTGACCTGACAGCGCCGGAACCCGCAGACATGGCTGACTGGAACGCAATGCGTCCGGTG
GGGCGTGAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References