Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pemK-chpS/PRK09812-MazE |
Location | 4752309..4752907 | Replicon | chromosome |
Accession | NZ_CP034337 | ||
Organism | Pseudomonas entomophila strain 2014 |
Toxin (Protein)
Gene name | pemK | Uniprot ID | - |
Locus tag | EI693_RS22030 | Protein ID | WP_125465503.1 |
Coordinates | 4752309..4752656 (-) | Length | 116 a.a. |
Antitoxin (Protein)
Gene name | chpS | Uniprot ID | - |
Locus tag | EI693_RS22035 | Protein ID | WP_189654498.1 |
Coordinates | 4752653..4752907 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EI693_RS22005 | 4747837..4748322 | - | 486 | WP_125465500.1 | peptidylprolyl isomerase | - |
EI693_RS22010 | 4748321..4748623 | + | 303 | WP_125466247.1 | DUF3565 domain-containing protein | - |
EI693_RS22015 | 4748656..4750746 | + | 2091 | WP_125465501.1 | phosphate acetyltransferase | - |
EI693_RS22020 | 4750830..4751549 | - | 720 | WP_125465502.1 | OmpA family protein | - |
EI693_RS22025 | 4751645..4752289 | - | 645 | WP_110994809.1 | MBL fold metallo-hydrolase | - |
EI693_RS22030 | 4752309..4752656 | - | 348 | WP_125465503.1 | type II toxin-antitoxin system ChpB family toxin | Toxin |
EI693_RS22035 | 4752653..4752907 | - | 255 | WP_189654498.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
EI693_RS22040 | 4753078..4753770 | - | 693 | WP_125465505.1 | HAMP domain-containing histidine kinase | - |
EI693_RS22045 | 4753767..4755374 | - | 1608 | WP_125465506.1 | response regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 116 a.a. Molecular weight: 12364.17 Da Isoelectric Point: 8.0308
>T115747 WP_125465503.1 NZ_CP034337:c4752656-4752309 [Pseudomonas entomophila]
MKRARFDRGDIVRINLDPTVDREQQGASRPALVLTPAMFNTSGLAVIVPISQGGDFSRHAGFAVTLSGAGTQTQGVMLCN
QLRTVDLEARGAKRIESVPEAVILDALARVQTLFD
MKRARFDRGDIVRINLDPTVDREQQGASRPALVLTPAMFNTSGLAVIVPISQGGDFSRHAGFAVTLSGAGTQTQGVMLCN
QLRTVDLEARGAKRIESVPEAVILDALARVQTLFD
Download Length: 348 bp
>T115747 NZ_CP034337:c4752656-4752309 [Pseudomonas entomophila]
TTGAAGCGGGCCAGGTTCGACAGAGGGGATATCGTCCGGATCAACCTGGACCCCACCGTCGATAGAGAACAGCAAGGTGC
TTCGCGCCCTGCGCTGGTGTTGACGCCCGCCATGTTCAATACCTCTGGTCTCGCGGTGATCGTGCCGATTTCACAAGGTG
GGGATTTCTCCCGGCACGCAGGTTTTGCAGTTACCCTGAGCGGCGCCGGTACCCAGACGCAAGGTGTGATGCTGTGCAAT
CAGCTACGCACGGTAGACCTTGAAGCGAGGGGCGCCAAGCGCATCGAATCCGTTCCCGAAGCCGTGATCCTGGACGCGCT
GGCGCGTGTTCAAACCCTCTTCGATTAA
TTGAAGCGGGCCAGGTTCGACAGAGGGGATATCGTCCGGATCAACCTGGACCCCACCGTCGATAGAGAACAGCAAGGTGC
TTCGCGCCCTGCGCTGGTGTTGACGCCCGCCATGTTCAATACCTCTGGTCTCGCGGTGATCGTGCCGATTTCACAAGGTG
GGGATTTCTCCCGGCACGCAGGTTTTGCAGTTACCCTGAGCGGCGCCGGTACCCAGACGCAAGGTGTGATGCTGTGCAAT
CAGCTACGCACGGTAGACCTTGAAGCGAGGGGCGCCAAGCGCATCGAATCCGTTCCCGAAGCCGTGATCCTGGACGCGCT
GGCGCGTGTTCAAACCCTCTTCGATTAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9292.75 Da Isoelectric Point: 5.7808
>AT115747 WP_189654498.1 NZ_CP034337:c4752907-4752653 [Pseudomonas entomophila]
MQIKIQQWGNSAAIRLPATVLKQMHLSVGSTLSLDTSGETLVLKPVRSKPEYRLEELMAQCDLTAPEPADMADWNAMRPV
GREA
MQIKIQQWGNSAAIRLPATVLKQMHLSVGSTLSLDTSGETLVLKPVRSKPEYRLEELMAQCDLTAPEPADMADWNAMRPV
GREA
Download Length: 255 bp
>AT115747 NZ_CP034337:c4752907-4752653 [Pseudomonas entomophila]
ATGCAGATCAAGATTCAGCAATGGGGCAACAGCGCAGCGATTCGTCTGCCGGCGACGGTCCTCAAGCAAATGCACCTGAG
CGTGGGGTCGACCCTGAGCCTGGATACTTCCGGCGAGACCTTGGTGCTCAAACCGGTCAGGTCGAAGCCCGAGTACCGGC
TGGAAGAGCTGATGGCGCAATGTGACCTGACAGCGCCGGAACCCGCAGACATGGCTGACTGGAACGCAATGCGTCCGGTG
GGGCGTGAAGCTTGA
ATGCAGATCAAGATTCAGCAATGGGGCAACAGCGCAGCGATTCGTCTGCCGGCGACGGTCCTCAAGCAAATGCACCTGAG
CGTGGGGTCGACCCTGAGCCTGGATACTTCCGGCGAGACCTTGGTGCTCAAACCGGTCAGGTCGAAGCCCGAGTACCGGC
TGGAAGAGCTGATGGCGCAATGTGACCTGACAGCGCCGGAACCCGCAGACATGGCTGACTGGAACGCAATGCGTCCGGTG
GGGCGTGAAGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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