Detailed information of TA system TA115745

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 3893453..3894153
• Replicon: chromosome
• Accession: NZ_CP034337
• Organism: Pseudomonas entomophila strain 2014

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: EI693_RS18150
• Protein ID: WP_125464901.1
• Coordinates: 3893857..3894153 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: EI693_RS18145
• Protein ID: WP_125464900.1
• Coordinates: 3893453..3893854 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EI693_RS18125	3888597..3889418	-	822	WP_125464896.1	transporter substrate-binding domain-containing protein	-
EI693_RS18130	3889503..3890432	-	930	WP_125464897.1	FAD-binding protein	-
EI693_RS18135	3890433..3891182	-	750	WP_125464898.1	electron transfer flavoprotein subunit beta/FixA family protein	-
EI693_RS18140	3891711..3893393	+	1683	WP_125464899.1	electron transfer flavoprotein-ubiquinone oxidoreductase	-
EI693_RS18145	3893453..3893854	-	402	WP_125464900.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
EI693_RS18150	3893857..3894153	-	297	WP_125464901.1	type II toxin-antitoxin system MqsR family toxin	Toxin
EI693_RS18155	3894248..3895573	-	1326	WP_125464902.1	MFS transporter	-
EI693_RS18160	3895635..3896120	-	486	WP_125464903.1	histidine kinase	-
EI693_RS18165	3896289..3896765	-	477	WP_125464904.1	sigma-70 family RNA polymerase sigma factor	-
EI693_RS18170	3896984..3898159	+	1176	WP_125464905.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (6-97)

Antitoxin

• Cro/C1-type helix-turn-helix domain (74-127)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11153.07 Da
• Isoelectric Point: 8.9903

>T115745 WP_125464901.1 NZ_CP034337:c3894153-3893857 [Pseudomonas entomophila]
MEKRMPHCPLDRVKALLAAKRVSPTSAALRGARSLGLDYPGMLDVISSLERTDFYKSMTCYTEHRVWQDVYRPLTAVGYV
YLKLSVVDDVLIVSFKEL

Nucleotide

• Length: 297 bp

>T115745 NZ_CP034337:c3894153-3893857 [Pseudomonas entomophila]
ATGGAAAAGAGAATGCCTCATTGCCCACTTGATCGGGTAAAAGCGCTGCTTGCTGCGAAGCGGGTCAGTCCGACTAGCGC
TGCATTAAGAGGTGCCAGGTCTCTGGGCCTGGATTACCCAGGAATGCTCGATGTGATCAGCAGTCTGGAACGCACTGACT
TTTACAAAAGCATGACCTGCTATACGGAACACCGCGTCTGGCAGGACGTATACCGTCCGCTCACGGCAGTCGGCTACGTT
TACCTGAAACTGTCAGTGGTCGATGACGTGCTCATCGTGTCCTTCAAGGAGCTGTAA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14664.61 Da
• Isoelectric Point: 4.9775

>AT115745 WP_125464900.1 NZ_CP034337:c3893854-3893453 [Pseudomonas entomophila]
MRCPICGGAELAPDTQDMPYRYKGESTLIQGVSGDYCSACGEAVLSHDEAMRVSEQMTAFERRVNATAVDPAFISAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALIKLFKLLDRHPELFEEVRTA

Nucleotide

• Length: 402 bp

>AT115745 NZ_CP034337:c3893854-3893453 [Pseudomonas entomophila]
ATGAGATGCCCGATCTGCGGTGGTGCGGAGCTTGCGCCAGATACTCAGGACATGCCCTATCGCTACAAAGGAGAGTCGAC
TCTGATCCAGGGCGTCAGCGGCGATTACTGCTCTGCCTGTGGTGAGGCGGTCCTGAGCCACGACGAAGCCATGCGTGTCA
GTGAGCAGATGACGGCCTTTGAGCGTCGGGTCAATGCGACTGCGGTCGATCCAGCTTTCATCAGCGCCGTGCGCAAGAAA
TTTGACCTGGACCAGCGCGAGGCAGGTGAGATTTTCGGTGGTGGGGTCAACGCTTTTTCCCGCTACGAAAATGGTAAAAC
CACGCCGCCAGTGGCGTTGATCAAGCTGTTCAAGCTGCTCGACCGCCACCCCGAGCTGTTCGAGGAAGTCAGGACCGCCT
GA