Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3893453..3894153 Replicon chromosome
Accession NZ_CP034337
Organism Pseudomonas entomophila strain 2014

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag EI693_RS18150 Protein ID WP_125464901.1
Coordinates 3893857..3894153 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag EI693_RS18145 Protein ID WP_125464900.1
Coordinates 3893453..3893854 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EI693_RS18125 3888597..3889418 - 822 WP_125464896.1 transporter substrate-binding domain-containing protein -
EI693_RS18130 3889503..3890432 - 930 WP_125464897.1 FAD-binding protein -
EI693_RS18135 3890433..3891182 - 750 WP_125464898.1 electron transfer flavoprotein subunit beta/FixA family protein -
EI693_RS18140 3891711..3893393 + 1683 WP_125464899.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
EI693_RS18145 3893453..3893854 - 402 WP_125464900.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EI693_RS18150 3893857..3894153 - 297 WP_125464901.1 type II toxin-antitoxin system MqsR family toxin Toxin
EI693_RS18155 3894248..3895573 - 1326 WP_125464902.1 MFS transporter -
EI693_RS18160 3895635..3896120 - 486 WP_125464903.1 histidine kinase -
EI693_RS18165 3896289..3896765 - 477 WP_125464904.1 sigma-70 family RNA polymerase sigma factor -
EI693_RS18170 3896984..3898159 + 1176 WP_125464905.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11153.07 Da        Isoelectric Point: 8.9903

>T115745 WP_125464901.1 NZ_CP034337:c3894153-3893857 [Pseudomonas entomophila]
MEKRMPHCPLDRVKALLAAKRVSPTSAALRGARSLGLDYPGMLDVISSLERTDFYKSMTCYTEHRVWQDVYRPLTAVGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T115745 NZ_CP034337:c3894153-3893857 [Pseudomonas entomophila]
ATGGAAAAGAGAATGCCTCATTGCCCACTTGATCGGGTAAAAGCGCTGCTTGCTGCGAAGCGGGTCAGTCCGACTAGCGC
TGCATTAAGAGGTGCCAGGTCTCTGGGCCTGGATTACCCAGGAATGCTCGATGTGATCAGCAGTCTGGAACGCACTGACT
TTTACAAAAGCATGACCTGCTATACGGAACACCGCGTCTGGCAGGACGTATACCGTCCGCTCACGGCAGTCGGCTACGTT
TACCTGAAACTGTCAGTGGTCGATGACGTGCTCATCGTGTCCTTCAAGGAGCTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14664.61 Da        Isoelectric Point: 4.9775

>AT115745 WP_125464900.1 NZ_CP034337:c3893854-3893453 [Pseudomonas entomophila]
MRCPICGGAELAPDTQDMPYRYKGESTLIQGVSGDYCSACGEAVLSHDEAMRVSEQMTAFERRVNATAVDPAFISAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALIKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT115745 NZ_CP034337:c3893854-3893453 [Pseudomonas entomophila]
ATGAGATGCCCGATCTGCGGTGGTGCGGAGCTTGCGCCAGATACTCAGGACATGCCCTATCGCTACAAAGGAGAGTCGAC
TCTGATCCAGGGCGTCAGCGGCGATTACTGCTCTGCCTGTGGTGAGGCGGTCCTGAGCCACGACGAAGCCATGCGTGTCA
GTGAGCAGATGACGGCCTTTGAGCGTCGGGTCAATGCGACTGCGGTCGATCCAGCTTTCATCAGCGCCGTGCGCAAGAAA
TTTGACCTGGACCAGCGCGAGGCAGGTGAGATTTTCGGTGGTGGGGTCAACGCTTTTTCCCGCTACGAAAATGGTAAAAC
CACGCCGCCAGTGGCGTTGATCAAGCTGTTCAAGCTGCTCGACCGCCACCCCGAGCTGTTCGAGGAAGTCAGGACCGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References