Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 533683..534185 Replicon chromosome
Accession NZ_CP034276
Organism Pectobacterium versatile strain 14A

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag EIP93_RS02420 Protein ID WP_039282578.1
Coordinates 533683..533937 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag EIP93_RS02425 Protein ID WP_039324900.1
Coordinates 533934..534185 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIP93_RS02400 529100..529939 + 840 WP_125232220.1 HTH-type transcriptional activator RhaS -
EIP93_RS02405 529964..530818 + 855 WP_040031929.1 helix-turn-helix domain-containing protein -
EIP93_RS02410 531010..532338 - 1329 WP_125232221.1 AAA family ATPase -
EIP93_RS02415 532335..533306 - 972 WP_125232222.1 reverse transcriptase family protein -
EIP93_RS02420 533683..533937 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
EIP93_RS02425 533934..534185 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
EIP93_RS02430 534260..535966 - 1707 WP_103972132.1 ABC transporter ATP-binding protein -
EIP93_RS02435 535963..536829 - 867 WP_125232223.1 ABC transporter permease -
EIP93_RS02440 536822..537781 - 960 WP_125232224.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T115643 WP_039282578.1 NZ_CP034276:c533937-533683 [Pectobacterium versatile]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T115643 NZ_CP034276:c533937-533683 [Pectobacterium versatile]
GTGAAGCTAATCTGGTCAGAAGAAGCATGGGAAGACTATCTGTACTGGCAGGACATCGATAAGCGGATGGTCAAAAAGAT
CAATGAATTAATAAAAGAAACGCGCAGAACACCTTTTGAAGGAAAAGGAAAACCAGAGCCACTTAAACATAACCTTGCTG
GTTTCTGGTCGCGCCGTATCACCGAAGAACATCGTCTGGTTTATGCCATCACCGATGACGCCATGATGATAGCCGCCTGC
CGCTACCACTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT115643 WP_039324900.1 NZ_CP034276:c534185-533934 [Pectobacterium versatile]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT115643 NZ_CP034276:c534185-533934 [Pectobacterium versatile]
ATGCGTACAATTAGCTACAGTGAAGCCCGACAAAATCTATCGGCGACCATGATGAAAACGGTCGAAGACCGTGCTCCTAT
TCTTATCACTCGACAGAATGGTGAAGCCTGCGTGCTTATGTCTCTGGAAGAGTATAACTCTCTAGAGGAAACCGCGTATT
TACTGCGTTCACCAGCCAATGCAAAAAGACTGATGAATTCAATCGAGAGCCTTAAGGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References