115639

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 91623..92974 Replicon chromosome
Accession NZ_CP034276
Organism Pectobacterium versatile strain 14A

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag EIP93_RS00390 Protein ID WP_125232112.1
Coordinates 91623..92663 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag EIP93_RS00395 Protein ID WP_116237915.1
Coordinates 92660..92974 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EIP93_RS00360 87021..87980 + 960 WP_103943153.1 bacteriophage abortive infection AbiH family protein -
EIP93_RS00365 88172..88459 - 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin -
EIP93_RS00370 88456..88707 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
EIP93_RS00375 88965..89870 + 906 WP_125232109.1 siderophore-interacting protein -
EIP93_RS00380 89905..90660 - 756 WP_125232110.1 thiol:disulfide interchange protein DsbG -
EIP93_RS00385 90939..91562 + 624 WP_125232111.1 LysE family translocator -
EIP93_RS00390 91623..92663 - 1041 WP_125232112.1 HipA domain-containing protein Toxin
EIP93_RS00395 92660..92974 - 315 WP_116237915.1 HipA N-terminal domain-containing protein Antitoxin
EIP93_RS00400 92959..93285 - 327 WP_125232113.1 helix-turn-helix domain-containing protein -
EIP93_RS00405 93444..94316 - 873 WP_125232114.1 LysR family transcriptional regulator -
EIP93_RS00410 94419..94928 + 510 WP_125232115.1 phenolic acid decarboxylase -
EIP93_RS00415 94985..96118 - 1134 WP_125232116.1 alkylhydroperoxidase domain protein -
EIP93_RS00420 96115..97149 - 1035 WP_103862830.1 putative FMN-dependent luciferase-like monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39562.56 Da        Isoelectric Point: 6.3862

>T115639 WP_125232112.1 NZ_CP034276:c92663-91623 [Pectobacterium versatile]
MTTCRILLTPLTHEEEMATGYSRKGLKHLAGSIHASPDLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLQDRAFIVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPDQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYISYERLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSEKLTKKLLADFIKEAECVESTYRDSFMP
AEAIDTTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T115639 NZ_CP034276:c92663-91623 [Pectobacterium versatile]
ATGACAACATGTCGAATTTTGCTGACACCGCTGACGCATGAAGAAGAGATGGCCACAGGTTATAGCCGTAAAGGTTTGAA
GCATCTGGCCGGATCAATACACGCCTCTCCAGACTTACGTTTCACCCGCCAGCAATTCATGCACGACCTGCCACAAACAC
AGAAAGGCATGAGTATTTCTGGCTATCAGCCCAAGATTCAGATGGTGTTACAAGATCGGGCATTTATCGTCGTTGATCAT
CAAGGGCTGTATATTCTTAAACCCTCTCCGATTGAATTTCCCCATTTGGCAGAAAACGAACATGCCACGATGACGCTAAT
GGCACGCCTGGGATTTGCCGTCCCGCCACACGGGTTGCTTCGTTTTAAACCGGATCAGGCTGATGACGAACCTGAGTTTG
CTTTCGTTATTAAGCGCTTCGACCGCGACGAAAAAACGGGCCACCCTATCCATCAGGAACAGTTGGACGGCGCGATGGGG
ATCGGGGAAAAATTCGGTAAAATACGTGCAGATGGCAGACAATACATCAGTTATGAGCGGTTGGCTTTATTCCTTAGCGA
GCACGTAAATGACAATATCGTCTTCAAAATAGATCTGTTCCGCCGCATCGCTTACGCCTACATGCTGGGTAACAACGATA
TGCACCTGCGTAATTTTGGGCTGATACATTCGCGCTCAGGCCAATTAATGCTGGCCCCTATTTATGACTTTGTTTCCGTC
GCCCCCTATCCCACCTATTTTTCTTCCTGCTTCATGGCACTACCGCTGCTGATTCAAGAAGAGGGGGATGAAGCGCTCGC
ACCCGGCTTTGAAACCGCGTACGGAGAGTATCTGGGTATGGATTTCATTCTGTTCGGACAGCGTATCGGACTGAGTGAAA
AGCTTACCAAAAAGCTACTGGCAGACTTCATCAAAGAAGCTGAATGCGTTGAATCAACCTATCGGGATTCCTTTATGCCT
GCGGAGGCGATTGATACGACGCTGCGGTGCTATCGACACCGCCTGAATCTTATGAGCATTCTCGATGCAGAACGGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11871.62 Da        Isoelectric Point: 8.3628

>AT115639 WP_116237915.1 NZ_CP034276:c92974-92660 [Pectobacterium versatile]
MRRQVKVYLYGVHIGQLSQDDKGYLFEYKKSYIGPPLSLSLPIQTGTFRSQTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDEA

Download         Length: 315 bp

>AT115639 NZ_CP034276:c92974-92660 [Pectobacterium versatile]
ATGCGCCGTCAAGTAAAGGTCTATCTTTACGGTGTCCACATCGGCCAGTTAAGTCAGGACGATAAAGGCTATTTGTTTGA
ATATAAAAAGTCCTACATCGGCCCGCCATTATCCTTGAGCCTACCGATACAGACCGGAACATTTCGCAGCCAGACATTAC
CGCCTTATTTTGCCTCATTAGCCCCCGAAGGCTGGCTCCGGCGCCAGTACAGCCAGCTACAGCATCTGGATGAGAAAGAC
CTGTTTGGTATCCTCATTCAAAACGGTAAGAATCTGATCGGCGCCGTACAACTGATTGCAGAGGATGAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References