Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3285508..3285766 Replicon chromosome
Accession NZ_CP034166
Organism Escherichia albertii strain 2014C-4015

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag AYR02_RS17180 Protein ID WP_000809168.1
Coordinates 3285508..3285660 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3285709..3285766 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYR02_RS17165 3280920..3282836 + 1917 WP_000516135.1 molecular chaperone DnaK -
AYR02_RS17170 3282925..3284055 + 1131 WP_001118445.1 molecular chaperone DnaJ -
AYR02_RS17175 3284318..3285430 - 1113 Protein_3081 IS4 family transposase -
AYR02_RS17180 3285508..3285660 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 3285709..3285766 + 58 - - Antitoxin
AYR02_RS17185 3286282..3287043 + 762 WP_124782903.1 hypothetical protein -
AYR02_RS17190 3287064..3288557 + 1494 WP_124782904.1 sulfatase-like hydrolase/transferase -
AYR02_RS17195 3288711..3289958 + 1248 WP_124782905.1 IS1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T115438 WP_000809168.1 NZ_CP034166:c3285660-3285508 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T115438 NZ_CP034166:c3285660-3285508 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT115438 NZ_CP034166:3285709-3285766 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References