Detailed information of TA system TA115404

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-ohsC/SymE(toxin)
• Location: 2929815..2930227
• Replicon: chromosome
• Accession: NZ_CP034162
• Organism: Escherichia albertii strain 06-3542

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: CCS91_RS14780
• Protein ID: WP_124866422.1
• Coordinates: 2929886..2930227 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	ohsC
Locus tag	-
Coordinates	2929815..2929891 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCS91_RS14770	2926723..2928312	+	1590	WP_113649427.1	type I restriction-modification system methyltransferase	-
CCS91_RS14775	2928309..2929658	+	1350	WP_113649426.1	restriction endonuclease subunit S	-
-	2929815..2929891	-	77	NuclAT_7	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_7	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_7	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_7	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_8	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_8	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_8	-	Antitoxin
-	2929815..2929891	-	77	NuclAT_8	-	Antitoxin
CCS91_RS14780	2929886..2930227	+	342	WP_124866422.1	endoribonuclease SymE	Toxin
CCS91_RS14785	2930389..2931768	+	1380	WP_124866423.1	5-methylcytosine-specific restriction endonuclease subunit McrB	-
CCS91_RS14790	2931768..2932814	+	1047	WP_072249344.1	5-methylcytosine-specific restriction endonuclease system specificity protein McrC	-
CCS91_RS14795	2932870..2933948	-	1079	Protein_2821	hypothetical protein	-
CCS91_RS14800	2934266..2934715	-	450	WP_164473971.1	Rpn family recombination-promoting nuclease/putative transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12338.18 Da
• Isoelectric Point: 8.4951

>T115404 WP_124866422.1 NZ_CP034162:2929886-2930227 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFVTGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVRDFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T115404 NZ_CP034162:2929886-2930227 [Escherichia albertii]
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGTCA
CCGGCACGGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAACTATCGGCGCGTAAACAAAAGCAGGTGCGGGATTTTATTGGGGTAATTGC
GGGTAAACAGAAAGTTGCGTAA

Antitoxin

Nucleotide

• Length: 77 bp

>AT115404 NZ_CP034162:c2929891-2929815 [Escherichia albertii]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin