Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2526414..2527744 Replicon chromosome
Accession NZ_CP034148
Organism Pantoea agglomerans strain L15

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag CBF16_RS12070 Protein ID WP_124890103.1
Coordinates 2526722..2527744 (+) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag CBF16_RS12065 Protein ID WP_124890102.1
Coordinates 2526414..2526725 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBF16_RS12040 2521878..2523260 + 1383 WP_124890098.1 FAD-binding protein -
CBF16_RS12045 2523273..2524103 + 831 WP_124890099.1 glycosyltransferase family 8 protein -
CBF16_RS12050 2524194..2525315 - 1122 WP_124890100.1 Gfo/Idh/MocA family oxidoreductase -
CBF16_RS12060 2526094..2526429 + 336 WP_124890101.1 helix-turn-helix transcriptional regulator -
CBF16_RS12065 2526414..2526725 + 312 WP_124890102.1 HipA N-terminal domain-containing protein Antitoxin
CBF16_RS12070 2526722..2527744 + 1023 WP_124890103.1 HipA domain-containing protein Toxin
CBF16_RS12075 2527870..2530047 - 2178 WP_124890451.1 catalase/peroxidase HPI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38506.04 Da        Isoelectric Point: 6.3468

>T115379 WP_124890103.1 NZ_CP034148:2526722-2527744 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENLPEELAFVIKRYDRTASDNARLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTIVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGINLPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENDAGNAPGINSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTEI

Download         Length: 1023 bp

>T115379 NZ_CP034148:2526722-2527744 [Pantoea agglomerans]
ATGAACTCAGAACGCTGCCTGATCACATTAAAACGGCTTAAAGAATCTGAGCTAAAAACTGGCTACTCAACAAAAGGCAT
CCGGCATCTGCTGGGTAGTCTGAATGTGGCTCTTAGCCTGCCGTTTACGCGTAGTCAGTTTATTCAGGAACTCCCTGAAC
GTCAGAAAGGCATGAGCATTTCAGGCTATCAACCCAAACTGTCGCTTCGCCTGGAAAAGGGAGAATTGGTGGTCGTCAGC
AATGATGGCACCTATATCCTGAAACCCTCTCCGGAAGAATATCCACACCTGGCAGAAAACGAGCATGCCACTATGTGCGT
TATGCAGCGTCTGAAATTTGACGTCCCCCCGTTCGGGCTGATGCCATTCAGACACGATGAAAATCTGCCAGAAGAACTGG
CGTTTGTCATTAAAAGGTATGACCGGACAGCGTCAGATAACGCGAGATTACATCAGGAACAGCTGGATGGCGCGATGGGT
CTCGGCGATAAATATGGCAGGATTGATAATCATAAAGCCATCAGTTACGAGAAAGCCGCTAAATTCCTGAATACCATAGT
GAACAGCAGCTTAAAGAGTAAACGTGACCTCTTTTTGCGCATCGTGTATGCCTATGTGCTGGGAAACAATGATTTTCATC
TGCGCAATATCGGGATTAACCTGCCTCCGCAGGGTTCACCCTGGCTGGCCCCGGTTTATGACTTTATCAGCGTTGTGCCC
TACCCTGCAGCGTTTGGAGAGTATTTAGCTTTGCCCCTGCTGGAACGTGAAGAAAATGATGCAGGAAACGCACCGGGGAT
CAATTCAGAGTACGGAGAATATCTGGGTGCAGACTTTATCCTGCTTGCCCAGGGTATGGATATTAATCCGACACTGGCAC
GAAAATGGCTTTCCGAGGTGGTGAGTCATCATCAGCTTATTATCGATACTTATAATGAAAGTCATATGCCTGAATCGCAG
CGGGAAGCCGTACTTGACTACGTGGCCCGAAGGATCACGTTACTGGCAGTGACCGAAATTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11705.50 Da        Isoelectric Point: 5.1019

>AT115379 WP_124890102.1 NZ_CP034148:2526414-2526725 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGHNGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp

>AT115379 NZ_CP034148:2526414-2526725 [Pantoea agglomerans]
ATGGCTCGAAAAATAGAGGTGTGGCTTTACAACACGCTGGCAGGGACGCTGAGTGAAGGGCATAACGGTTATACTTTCTG
CTACCTGCCTACTTATGTCGGCTGTGCGATATCTCTCAGCATGCCGGTAAGACCTGAGCCCTATTTAAGTGAAGAGCTAC
ATCCCTTCTTTAAAGGTTTAGCGCCGGAAGGCTGGTTGCGAAAACGCTATTCTGAAATTCAAAAAATTGATGATAAAGAT
CTGTTCGGCTTACTGATGGAAAATGGCAACGATTTGCTTGGGGCAGTCGTCTTTAAAGAGATAACATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References