Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3575590..3576405 Replicon chromosome
Accession NZ_CP034105
Organism Proteus sp. GOKU

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag EHE21_RS16355 Protein ID WP_194951258.1
Coordinates 3575932..3576405 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag EHE21_RS16350 Protein ID WP_088494531.1
Coordinates 3575590..3575925 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHE21_RS16330 3571275..3572699 + 1425 WP_088494534.1 aspartate ammonia-lyase -
EHE21_RS16335 3572858..3574183 + 1326 WP_194951256.1 anaerobic C4-dicarboxylate transporter -
EHE21_RS16340 3574368..3574940 + 573 WP_194951257.1 transcriptional regulator -
EHE21_RS16350 3575590..3575925 + 336 WP_088494531.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
EHE21_RS16355 3575932..3576405 + 474 WP_194951258.1 type II toxin-antitoxin system YhaV family toxin Toxin
EHE21_RS16360 3576715..3577362 + 648 WP_194951259.1 CPBP family intramembrane metalloprotease -
EHE21_RS16365 3577665..3578300 + 636 WP_194951260.1 DUF1449 family protein -
EHE21_RS16370 3578388..3580583 + 2196 WP_194951261.1 flotillin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18683.23 Da        Isoelectric Point: 8.9888

>T115243 WP_194951258.1 NZ_CP034105:3575932-3576405 [Proteus sp. GOKU]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKQADTKIFAHVLKSIVNITNDTRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDH

Download         Length: 474 bp

>T115243 NZ_CP034105:3575932-3576405 [Proteus sp. GOKU]
ATGGATTTCCCTACAGATTTGAATGGATGGACAATCTATGCACATCCTTGCTTTAAACAACAATATGATGAATTACTACA
AAAAGTTGAAGCACTGAAAAAAAAATATCCCGAAGATTATCAGAAACAAGCAGATACAAAAATTTTTGCTCATGTATTGA
AATCTATAGTAAACATCACAAATGATACACGGGCACCAGAGTTTAGGTTGGGTAATACTTTAGGAGAAGAAAATAAAAAT
TGGTCACGAATTAAATTAGTAAATGGAAGATATCGTTTATTTTTTAGATTCAGTTTTAAGGAAAAGATCATCATTCTGGC
ATGGATAAATGATAATGATACTTTGCGAACTTATGGCAATAAAACTGATGCTTACCGAGTCTTTGAGAAAAAACTAAAGA
AAGGTCACCCGCCTAAAAATTGGAATGATTTATTTAGTGACTGTATAAATGAAGCTGACTGTCAGGATCATTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12311.73 Da        Isoelectric Point: 4.4244

>AT115243 WP_088494531.1 NZ_CP034105:3575590-3575925 [Proteus sp. GOKU]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSKDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT115243 NZ_CP034105:3575590-3575925 [Proteus sp. GOKU]
ATGCTAACCCACGTTTGCACTGACAACATCGCTCTTGAAGCTGATTCAAAAATAACAGAACGTCATCAAACCACAATTCC
CGCGTCAATTAGAGAAGCTCTACATCTTAGTGGTGGAGATCGTATTCACTACAAATTACTGAGCACTGGTGATGTACTTA
TCTCACGTCACAGCGATGGATCAAAAGATCCTGTTATGGCATCGTTTCTTAATTTTCTCGCTCAAGATATAACTAATCAT
CCTCAAACCATTCAACCTCTCGATATATCTCGCGGTTTTGAATTAGTTGAAGGTATGGATATCAACCTTGACGATGACAT
CACCGATAACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References