Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2555269..2555453 Replicon chromosome
Accession NZ_CP034102
Organism Staphylococcus aureus strain O267

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SaO267_RS13510 Protein ID WP_000482647.1
Coordinates 2555346..2555453 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2555269..2555329 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO267_RS13485 2550723..2550890 - 168 WP_041204334.1 hypothetical protein -
SaO267_RS13495 2551121..2552854 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
SaO267_RS13500 2552879..2554642 - 1764 WP_001064817.1 ABC transporter ATP-binding protein/permease -
- 2555269..2555329 + 61 - - Antitoxin
SaO267_RS13510 2555346..2555453 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SaO267_RS13515 2555586..2555972 - 387 WP_000779350.1 flippase GtxA -
SaO267_RS13520 2556240..2557382 + 1143 WP_001176868.1 glycerate kinase -
SaO267_RS13525 2557442..2558101 + 660 WP_000831299.1 hypothetical protein -
SaO267_RS13530 2558287..2559498 + 1212 WP_001191928.1 multidrug effflux MFS transporter -
SaO267_RS13535 2559621..2560094 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T115233 WP_000482647.1 NZ_CP034102:c2555453-2555346 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T115233 NZ_CP034102:c2555453-2555346 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT115233 NZ_CP034102:2555269-2555329 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References