Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2407046..2407230 Replicon chromosome
Accession NZ_CP034098
Organism Staphylococcus aureus strain 80wphwpl_v1

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag EHS18_RS12235 Protein ID WP_000482648.1
Coordinates 2407123..2407230 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2407046..2407106 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHS18_RS12210 2402556..2402723 - 168 Protein_2273 hypothetical protein -
EHS18_RS12220 2402954..2404687 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
EHS18_RS12225 2404712..2406475 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2407046..2407106 + 61 - - Antitoxin
EHS18_RS12235 2407123..2407230 - 108 WP_000482648.1 type I toxin-antitoxin system Fst family toxin Toxin
EHS18_RS12240 2407364..2407750 - 387 WP_000779351.1 flippase GtxA -
EHS18_RS12245 2408018..2409160 + 1143 WP_001176855.1 glycerate kinase -
EHS18_RS12250 2409220..2409879 + 660 WP_000831298.1 membrane protein -
EHS18_RS12255 2410061..2411272 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
EHS18_RS12260 2411395..2411868 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4026.79 Da        Isoelectric Point: 10.4935

>T115216 WP_000482648.1 NZ_CP034098:c2407230-2407123 [Staphylococcus aureus]
MFNLLIEIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T115216 NZ_CP034098:c2407230-2407123 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGAAATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT115216 NZ_CP034098:2407046-2407106 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References