Detailed information of TA system TA115214

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-sprA1AS/-
• Location: 2122026..2122223
• Replicon: chromosome
• Accession: NZ_CP034098
• Organism: Staphylococcus aureus strain 80wphwpl_v1

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: EHS18_RS10680
• Protein ID: WP_073392962.1
• Coordinates: 2122119..2122223 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2122026..2122064 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EHS18_RS10660	2118201..2118866	-	666	WP_001024099.1	SDR family oxidoreductase	-
EHS18_RS10665	2119018..2119338	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
EHS18_RS10670	2119340..2120320	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
EHS18_RS10675	2120586..2121677	+	1092	WP_000495684.1	hypothetical protein	-
-	2122026..2122064	+	39	-	-	Antitoxin
EHS18_RS10680	2122119..2122223	-	105	WP_073392962.1	hypothetical protein	Toxin
EHS18_RS10690	2122903..2123061	+	159	WP_001792784.1	hypothetical protein	-
EHS18_RS10700	2123720..2124577	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
EHS18_RS10705	2124645..2125427	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T115214 WP_073392962.1 NZ_CP034098:c2122223-2122119 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T115214 NZ_CP034098:c2122223-2122119 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 39 bp

>AT115214 NZ_CP034098:2122026-2122064 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin