Detailed information of TA system TA115208

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1832690..1832870
• Replicon: chromosome
• Accession: NZ_CP034098
• Organism: Staphylococcus aureus strain 80wphwpl_v1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EHS18_RS09000
• Protein ID: WP_001801861.1
• Coordinates: 1832690..1832785 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1832813..1832870 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EHS18_RS08965	1827834..1828460	+	627	WP_000669038.1	hypothetical protein	-
EHS18_RS08970	1828501..1828845	+	345	WP_000627550.1	DUF3969 family protein	-
EHS18_RS08975	1828943..1829515	+	573	WP_000414222.1	hypothetical protein	-
EHS18_RS08980	1829664..1831031	-	1368	WP_001093574.1	FRG domain-containing protein	-
EHS18_RS08985	1831031..1831600	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
EHS18_RS08990	1831793..1832239	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
EHS18_RS09000	1832690..1832785	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1832813..1832870	-	58	-	-	Antitoxin
EHS18_RS09005	1832908..1833009	+	102	WP_001791232.1	hypothetical protein	-
EHS18_RS09010	1833184..1833627	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
EHS18_RS09015	1833627..1834070	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
EHS18_RS09020	1834070..1834512	-	443	Protein_1710	DUF1433 domain-containing protein	-
EHS18_RS09025	1835037..1837457	+	2421	WP_000182551.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T115208 WP_001801861.1 NZ_CP034098:1832690-1832785 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T115208 NZ_CP034098:1832690-1832785 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT115208 NZ_CP034098:c1832870-1832813 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin