Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2266084..2266300 Replicon chromosome
Accession NZ_CP033987
Organism Staphylococcus aureus strain P2D1C1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EFD76_RS11455 Protein ID WP_001802298.1
Coordinates 2266196..2266300 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2266084..2266139 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD76_RS11435 2262290..2262955 - 666 WP_001024095.1 SDR family oxidoreductase -
EFD76_RS11440 2263107..2263427 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EFD76_RS11445 2263429..2264406 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
EFD76_RS11450 2264672..2265763 + 1092 WP_156668041.1 transcriptional regulator -
- 2266084..2266139 + 56 - - Antitoxin
EFD76_RS11455 2266196..2266300 - 105 WP_001802298.1 hypothetical protein Toxin
EFD76_RS11460 2266980..2267138 + 159 WP_001792784.1 hypothetical protein -
EFD76_RS11465 2267796..2268653 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
EFD76_RS11470 2268721..2269503 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T114808 WP_001802298.1 NZ_CP033987:c2266300-2266196 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T114808 NZ_CP033987:c2266300-2266196 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT114808 NZ_CP033987:2266084-2266139 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References